Evidence map›Paper›PMID 32985923›Full record

ArticleGut microbes2020

Metagenomic analysis reveals distinct patterns of gut lactobacillus prevalence, abundance, and geographical variation in health and disease.

Tarini Shankar Ghosh, Jerome Arnoux, Paul W O'Toole

Abstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
  2. Virulence · 2026
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  17. Journal of clinical microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tarini Shankar GhoshDepartment: School of Microbiology and APC Microbiome Ireland Institution, University College Cork , Cork, Ireland.ORCID 0000-0001-9570-0365
Jerome ArnouxDepartment: School of Microbiology and APC Microbiome Ireland Institution, University College Cork , Cork, Ireland.
Paul W O'TooleDepartment: School of Microbiology and APC Microbiome Ireland Institution, University College Cork , Cork, Ireland.ORCID 0000-0001-5377-0824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactobacilli are exploited extensively for food fermentation and biotechnology. Some food and gut isolates have been developed as probiotics, for which species that may be commensal to the human host are considered desirable. However, the robustness of defining original niches for lactobacilli - food, environment, the gut - is questionable, and culture-independent analyses of prevalence in different human populations is lacking. Here we analyzed the abundance of lactobacilli in 6,154 subjects from a database of highly curated fecal shotgun metagenomics data spanning 25 nationalities, with ages ranging from infancy to 102 years. Twenty-five species were detected, which we assigned into low, medium, and high prevalence groups. The microbiome of apparently healthy individuals could be categorized into 6 clusters or Lactobacillotypes (LbTypes), with three of the Lbtypes being dominated by

Indexed as

DiseaseGastrointestinal MicrobiomeHealthMetagenomeAdolescentAdultAgedAged, 80 and overAge FactorsBody Mass IndexChildChild, PreschoolDiabetes Mellitus, Type 2DietFecesFemaleage variationsGut microbiomelactobacillusprobioticregional variations

Identifiers

PMID32985923
PMCPMC7524322

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.