ArticleHeredity2021
Balancing selection versus allele and supertype turnover in MHC class II genes in guppies.
Article in Heredity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Adaptive Genetic Variation in Black-and-White Snub-Nosed Monkeys (Ecology and evolution · 2026Article
- Sex-dependent effects of infection on guppy reproductive fitness and offspring parasite resistance.The Journal of animal ecology · 2025Article
- MHC Diversity Across Time and Space.Ecology and evolution · 2025Review
- Widespread Adaptive Introgression of Major Histocompatibility Complex Genes across Vertebrate Hybrid Zones.Molecular biology and evolution · 2024Article
- Balancing selection shapes population differentiation of major histocompatibility complex genes in wild golden snub-nosed monkeys.Current zoology · 2024Article
- Immunogenetics, sylvatic plague and its vectors: insights from the pathogen reservoir Mastomys natalensis in Tanzania.Immunogenetics · 2023Article
- Genetic variation at innate and adaptive immune genes - contrasting patterns of differentiation and local adaptation in a wild gull.Heredity · 2023Article
- Characterization and Comparative Analysis of Chloroplast Genomes of Medicinal HerbInternational journal of molecular sciences · 2023Article
- Evolution of MHC IIB Diversity Across Cichlid Fish Radiations.Genome biology and evolution · 2023Review
- What do orange spots reveal about male (and female) guppies? A test using correlated responses to selection.Evolution; international journal of organic evolution · 2021Article
- Functional immunogenetic variation, rather than local adaptation, predicts ectoparasite infection intensity in a model fish species.Molecular ecology · 2021Article
- Balancing selection, genetic drift, and human-mediated introgression interplay to shape MHC (functional) diversity in Mediterranean brown trout.Ecology and evolution · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selection pressure from parasites is thought to be a major force shaping the extreme polymorphism of the major histocompatibility complex (MHC) genes, but the modes and consequences of selection remain unclear. Here, we analyse MHC class II and microsatellite diversity in 16 guppy (Poecilia reticulata) populations from two islands (Trinidad and Tobago) that have been separated for at least 10 ky. Within-population MHC diversity was high, but allele sharing was limited within islands and even lower between islands, suggesting relatively fast turnover of alleles. Allelic lineages strongly supported in phylogenetic analyses tended to be island-specific, suggesting rapid lineage sorting, and an expansion of an allelic lineage private to Tobago was observed. New alleles appear to be generated locally at a detectably high frequency. We did not detect a consistent signature of local adaptation, but F
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.