ArticleScientific reports2020
Gender differences in adolescent sleep neurophysiology: a high-density sleep EEG study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Sex differences in electrical activity of the brain during sleep: a systematic review of electroencephalographic findings across the human lifespan.Biomedical engineering online · 2025Pooled it
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- Nonlinear association between sleep duration and thyroid hormone levels in patients with thyroid cancer.Scientific reports · 2026Article
- Differences in sleep spindles and polysomnography in humans: a meta-analysis on the influence of age, sex, and cognitive ability.Frontiers in sleep · 2026Review
- Using a wearable EEG device to examine age trends in sleep macro- and micro-architecture across adolescence.bioRxiv : the preprint server for biology · 2025Article
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- Chronotype and depression in adolescence: Results from a UK birth cohort study.JCPP advances · 2025Article
- Age-related and sex-specific trends in sleep quality in children and adolescents.Frontiers in neuroscience · 2025Article
- Evaluation of wakefulness electroencephalogram in OSA patients.Sleep & breathing = Schlaf & Atmung · 2024Article
- A Complementary Dual-Mode Ion-Electron Conductive Hydrogel Enables Sustained Conductivity for Prolonged Electroencephalogram Recording.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Neural Dynamics Associated with Biological Variation in Normal Human Brain Regions.Entropy (Basel, Switzerland) · 2024Article
- Differential effects of the stress peptides PACAP and CRF on sleep architecture in mice.NPP - digital psychiatry and neuroscience · 2024Article
- The association between cortical gyrification and sleep in adolescents and young adults.Sleep · 2024Article
- Sex and Sleep Disruption as Contributing Factors in Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2024Review
- Effects of gender and age on sleep EEG functional connectivity differences in subjects with mild difficulty falling asleep.Frontiers in psychiatry · 2024Article
- The association between cortical gyrification and sleep in adolescents and young adults.bioRxiv : the preprint server for biology · 2023Article
- Electronic Design for Wearables Devices Addressed from a Gender Perspective: Cross-Influences and a Methodological Proposal.Sensors (Basel, Switzerland) · 2023Article
- Sleep Duration in Adolescence and Its Prenatal, Perinatal, and Health Determinants in a Large Population-based Cohort Followed from Birth.Sleep science (Sao Paulo, Brazil) · 2023Article
- Interneuronal GluK1 kainate receptors control maturation of GABAergic transmission and network synchrony in the hippocampus.Molecular brain · 2023Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During adolescence, differences between males and females in physiology, behavior and risk for psychopathology are accentuated. The goal of the current study was to examine gender differences in sleep neurophysiology using high-density sleep EEG in early adolescence. We examined gender differences in sleep EEG power and coherence across frequency bands for both NREM and REM sleep in a sample of 61 adolescents (31 girls and 30 boys; mean age = 12.48; SD = 1.34). In addition, sleep spindles were individually detected and characterized. Compared to boys, girls had significantly greater spindle activity, as reflected in higher NREM sigma power, spindle amplitude, spindle frequency and spindle density over widespread regions. Furthermore, power in higher frequency bands (16.2-44 Hz) was larger in girls than boys in a state independent manner. Oscillatory activity across frequency bands and sleep states was generally more coherent in females as compared to males, suggesting greater connectivity in females. An exception to this finding was the alpha band during NREM and REM sleep, where coherence was higher (NREM) or not different (REM) in boys compared to girls. Sleep spindles are generated through thalamocortical circuits, and thus, the greater spindle activity across regions in females may represent a stronger thalamocortical circuit in adolescent females as compared to males. Moreover, greater global connectivity in females may reflect functional brain differences with implications for cognition and mental health. Given the pronounced gender differences, our study highlights the importance of taking gender into account when designing and interpreting studies of sleep neurophysiology.
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