ArticleNeural regeneration research2021
Anxiety, depression, and quality of life in Parkinson's disease: the implications of multidisciplinary treatment.
Article in Neural regeneration research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Exercise as a potent antidepressant intervention in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials.Frontiers in psychology · 2026Pooled it
- Effectiveness of Telemedicine Interventions on Motor and Nonmotor Outcomes in Parkinson Disease: Systematic Review and Network Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- The Effectiveness of Inpatient Rehabilitation in Parkinson's Disease: A Systematic Review of Recent Studies.Journal of Parkinson's disease · 2024Pooled it
- Efficacy and safety evaluation of intravenous esketamine in alleviating perioperative depressive symptoms in Parkinson's disease: a randomized controlled trial.BMC anesthesiology · 2026Trial
- Interpersonal Psychotherapy for the Treatment of Depression in Parkinson's Disease: Results of a Randomized Controlled Trial.Movement disorders : official journal of the Movement Disorder Society · 2025Trial
- Effects of deep brain stimulation on functional autonomy and quality of life in Parkinson's disease: A systematic review and meta-analysis.Journal of Parkinson's disease · 2026Review
- Altered light-dark phase-dependent behavioral responses and suprachiasmatic nucleus pathology in an α-synuclein rat model of Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Intensive multidisciplinary rehabilitation modulates serumFrontiers in cellular neuroscience · 2026Article
- Non-motor correlates of anxiety inFrontiers in neuroscience · 2026Article
- Enhancing gait training with anti-gravity treadmill 'Alter-G' in patients with Parkinson's disease.PloS one · 2026Article
- Multidimensional factors of health-related quality of life in parkinson's disease using ensemble learning and network analysis.Scientific reports · 2025Article
- Effects of Exercise on Balance, Gait Speed, Quality of Life, and Symptom Relief Among Older Adults with Parkinson's Disease: A Meta-Analysis of Randomized Controlled Trials (RCTs).Healthcare (Basel, Switzerland) · 2025Review
- The Role of Cognitive Reserve in Coping with Subjective Cognitive Complaints: An Exploratory Study of People with Parkinson's Disease (PwPD).Brain sciences · 2025Article
- The Prevalence of Depression Among Parkinson's Disease Patients in Saudi Arabia: A Cross-Sectional Study.Neuropsychiatric disease and treatment · 2025Article
- Association between the length of stay in rehabilitation and mortality among the adults with Parkinson's disease: 2009-2019 Korean National Health Insurance Service Databases.Frontiers in aging neuroscience · 2024Article
- Longitudinal faster anxiety progression ofFrontiers in neuroscience · 2024Article
- High-frequency multimodal training with a focus on Tai Chi in people with Parkinson's disease: a pilot study.Frontiers in aging neuroscience · 2024Article
- Article
- Towards improved access to device-aided therapies in advanced PD: the importance of cooperation of different disciplines.Journal of neural transmission (Vienna, Austria : 1996) · 2023Review
- Association of Depression With Early Occurrence of Postural Instability in Parkinson's Disease.Journal of movement disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anxiety and depression in Parkinson's disease (PD) reduce well-being of the patients. Emotional alterations influence motor skills and cognitive performance; moreover, they contribute significantly and independently to worsen rehabilitative treatment response. We investigated anxiety, depression, and quality of life in PD patients subjected to multidisciplinary rehabilitative training. The self-controlled study included 100 PD patients (49 males and 51 females with the mean age of 64.66 years) admitted to 60 days hospitalization rehabilitative program, between January 2017 and December 2018. Motor, cognitive, linguistic abilities, and functional independence were evaluated at admission (T0 baseline visit) and 60 days after (T1) the multidisciplinary rehabilitation including motor exercises, speech therapies, and cognitive intervention. The multidisciplinary rehabilitation improved functional status in PD patients and exerted its positive effects on mood, motor abilities, autonomy in the activities of daily life, perception of quality of life, cognitive performance and speech skills. Non-motor symptoms may worsen severe disability and reduce quality of life. They are often poorly recognized and inadequately treated. Nonetheless, multidisciplinary rehabilitative training represents an optimal strategy to improve disease management. The study was approved by Istituito di Ricovero e Cura a Carattere Scientifico (IRCCS) Centro Neurolesi "Bonino-Pulejo" Ethical Committee (approval No. 6/2016) in June 2016.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.