Evidence map›Paper›PMID 32985291›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2021

Virtual 2D angiography from four-dimensional digital subtraction angiography (4D-DSA): A feasibility study.

Jay F Yu, Leland Pung, Hataka Minami, Kerstin Mueller, Rajkamal Khangura, Robert Darflinger, Steven W Hetts, Daniel L Cooke

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Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Four-dimensional digital subtraction angiography for the vascular anatomical diagnosis of dural arteriovenous malformation: Comparison with the conventional method.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
  2. Double C-Arm Digital Subtraction Angiography Guidance During Transjugular Intrahepatic Portosystemic Shunt Placement.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jay F YuDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.ORCID https://orcid.org/0000-0003-4015-2052
Leland PungSiemens Medical Solutions Inc., Malvern, PA, USA.
Hataka MinamiSiemens Medical Solutions Inc., Malvern, PA, USA.
Kerstin MuellerSiemens Medical Solutions Inc., Malvern, PA, USA.
Rajkamal KhanguraDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Robert DarflingerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Steven W HettsDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.ORCID https://orcid.org/0000-0001-5885-7259
Daniel L CookeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDigital subtraction angiography (DSA) remains the gold standard for angiographic evaluation of cerebrovascular pathology, however, multiple acquisitions requiring additional time and radiation are often needed. In contrast, 3D-DSA provides volumetric information from a single injection but neglects temporal information. Four-dimensional-DSA (4D-DSA) combines temporal information of 2D-DSA with volumetric information of 3D-DSA to provide time-resolved tomographic 3D reconstructions, potentially reducing procedure time and radiation. This work evaluates the diagnostic quality of virtual single-frame 4D-DSA relative to 2D-DSA images by assessing clinicians' ability to evaluate cerebrovascular pathology.

methodsSingle-frame images of four projections from 4D-DSA and their corresponding 2D-DSA images (n = 15) were rated by two neurointerventional radiologists. Images were graded based on diagnostic quality (0 = non-diagnostic, 1 = poor, 2 = acceptable, 3 = good). Dose area product (DAP) for each case was recorded for all 2D-DSA, 4D-DSA acquisitions, and the overall procedure.

resultsThe mean diagnostic quality of all four 4D-DSA projections from both raters was 1.75 while the mean of 2D-DSA projections was 2.8. Student's t-test revealed significant difference in diagnostic quality between 4D-DSA and 2D-DSA at all four projections (p < 0.001). On average 4D-DSA acquisitions accounted for 30% dose compared to the overall average aggregated dose per procedure.

conclusionsThe difference in image quality between virtual single-frame 4D-DSA and their respective 2D-DSA images is statistically significant. Furthermore, 4D-DSA acquisitions require less radiation dose than conventional procedures with 2D-DSA acquisitions.

Indexed as

Intracranial Arteriovenous MalformationsAngiography, Digital SubtractionFeasibility StudiesHumansImaging, Three-Dimensionalbrain arteriovenous malformation(s)Digital subtraction angiographydose area productdural arteriovenous fistulas(s)intracerebral hemorrhage

Identifiers

PMID32985291
PMCPMC8050537

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.