Evidence map›Paper›PMID 32985156›Full record

ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2020

[Correlation between transient receptor potential canonical channel with heart and kidney injure of rat model of obstructive sleep apnea hypopnea syndrome].

Wen Wen, Qiaoling Yao, Yulan Chen, Zhiqiang Li, Xiaojing Sun, Yu Li, Junshi Zhang, Zhulipiya Simayi, Xinjuan Xu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wen WenDepartment of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Qiaoling YaoDepartment of Physiology, Preclinical Medicine Collage of Xinjiang Medical University, Urumqi 830054, China.
Yulan ChenDepartment of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Zhiqiang LiClinical Medical Research Institute, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Xiaojing SunDepartment of Critical Medicine, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China.
Yu LiSecond Department of General Internal Medicine, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Junshi ZhangDepartment of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Zhulipiya SimayiDepartment of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Xinjuan XuDepartment of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Xinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the expression of transient receptor potential canonical channels (TRPCs) in the heart and kidney of rat model of obstructive sleep apnea hypopnea syndrome (OSAHS).

methodsEighteen male SD rats were randomly assigned to intermittent hypoxia (IH) group (

resultsThe mRNA expressions of TRPC3/TRPC4/TRPC5 in heart tissues of IH group were increased significantly compared with the control group (all

conclusionsThe IH rat model shows that TRPC5 channel is likely to be involved in the OSAHS induced pathophysiological changes in the myocardium and may become a target to prevent OSAHS related cardiac damage.

Indexed as

Heart InjuriesKidneySleep Apnea, ObstructiveTRPC Cation ChannelsAnimalsMaleRandom AllocationRatsRats, Sprague-DawleyRNA, MessengerRNA, MessengerTRPC Cation ChannelsCase-control studiesDisease models, animalHeart/metabolismHypoxia/pathologyKidney/metabolismProteinsSleep apnea syndromes/physiopathologyTransient receptor potential channels/metabolism

Identifiers

PMID32985156
PMCPMC8800798
OpenAlexW3088203662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.