Evidence map›Paper›PMID 32985131›Full record

ArticleObesity (Silver Spring, Md.)2020

Can Electronic Health Records Validly Estimate the Effects of Health System Interventions Aimed at Controlling Body Weight?

John A Gallis, Kristie Kusibab, Joseph R Egger, Maren K Olsen, Sandy Askew, Dori M Steinberg, Gary Bennett

Open access · greenAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

John A GallisDepartment of Biostatistics & Bioinformatics, Duke University, Durham, North Carolina, USA.ORCID 0000-0003-1921-8424
Kristie Kusibab *PharPoint Research, Inc., Durham, North Carolina, USA.
Joseph R EggerDuke Global Health Institute, Duke University, Durham, North Carolina, USA.ORCID 0000-0002-6885-5318
Maren K OlsenDepartment of Biostatistics & Bioinformatics, Duke University, Durham, North Carolina, USA.ORCID 0000-0002-9540-2103
Sandy AskewDuke Global Health Institute, Duke University, Durham, North Carolina, USA.
Dori M SteinbergDuke Global Health Institute, Duke University, Durham, North Carolina, USA.ORCID 0000-0001-7588-4216
Gary BennettDuke Global Health Institute, Duke University, Durham, North Carolina, USA.ORCID 0000-0002-4740-9175
Duke University · USCancer Research And Biostatistics · US

Funding

A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary CareR18DK109518 · NIDDK · DUKE UNIVERSITY · PI BENNETT, GARY G · 2016 to 2020
$3.3M
New Media Obesity Treatment in Community Health CentersR01DK093829 · NIDDK · DUKE UNIVERSITY · PI BENNETT, GARY G · 2012 to 2016
$3.2M
Community Based Obesity Prevention Among Black WomenR01DK078798 · NIDDK · DUKE UNIVERSITY · PI BENNETT, GARY G · 2008 to 2012
$3.0M
NIDDK NIH HHS R01 DK078798NIDDK NIH HHS R01 DK093829NIDDK NIH HHS R18 DK109518
6 · The paper itself

Abstract

objectiveThis study aimed to compare weight collected at clinics and recorded in the electronic health record (EHR) with primary study-collected trial weights to assess the validity of using EHR data in future pragmatic weight loss or weight gain prevention trials.

methodsFor both the Track and Shape obesity intervention randomized trials, clinic EHR weight data were compared with primary trial weight data over the same time period. In analyzing the EHR weights, intervention effects were estimated on the primary outcome of weight (in kilograms) with EHR data, using linear mixed effects models.

resultsEHR weight measurements were higher on average and more variable than trial weight measurements. The mean difference and 95% CI were similar at all time points between the estimates using EHR and study-collected weights.

conclusionsThe results of this study can be used to help guide the planning of future pragmatic weight-related trials. This study provides evidence that body weight measurements abstracted from the EHR can provide valid, efficient, and cost-effective data to estimate treatment effects from randomized clinical weight loss and weight management trials. However, care should be taken to properly understand the data-generating process and any mechanisms that may affect the validity of these estimates.

Indexed as

Body WeightElectronic Health RecordsHumansInternet-Based InterventionLearning Health SystemMiddle AgedResearch Design

Identifiers

PMID32985131
PMCPMC8351620
OpenAlexW3089305668

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.