Evidence map›Paper›PMID 32985080›Full record

Trial reportTropical medicine & international health : TM & IH2020

Predictors of receiving a diagnosis, referral and treatment of depression in people on antiretroviral therapy in South African primary care: a secondary analysis of data from a randomised trial.

B Zani, L Fairall, I Petersen, N Folb, A Bhana, G Thornicroft, J Hanass-Hancock, C Lund, M Bachmann, CobALT Research Team

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Tropical medicine & international health : TM & IH, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.0field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

B ZaniKnowledge Translation Unit, University of Cape Town Lung Institute, Cape Town, South Africa.
L FairallKnowledge Translation Unit, University of Cape Town Lung Institute, Cape Town, South Africa.
I PetersenCentre for Rural Health, University of KwaZulu-Natal, Durban, South Africa.
N FolbKnowledge Translation Unit, University of Cape Town Lung Institute, Cape Town, South Africa.
A BhanaCentre for Rural Health, University of KwaZulu-Natal, Durban, South Africa.
G ThornicroftCentre for Global Mental Health, King's College London, London, UK.
J Hanass-HancockHIV Prevention Research Unit, South African Medical Research Council, Durban, South Africa.
C LundCentre for Global Mental Health, King's College London, London, UK.
M BachmannNorwich Medical School, University of East Anglia, Norwich, UK.
CobALT Research Team
University of Cape Town · ZAUniversity of KwaZulu-Natal · ZAKing's College London · GBSouth African Tuberculosis Vaccine Initiative · ZAUniversity of East Anglia · GB

Funding

South African Medical Research Council Clinical Trials Unit (MRC CTU)UM1AI069422 · NIAID · MEDICAL RESEARCH COUNCIL OF SOUTH AFRICA · PI ABDULLAH, MAHOMED FAREED ABOOBAKER, GOGA, AMEENA · 2012 to 2020
$37.4M
COBALT: Comorbid Affective Disorders, AIDS/HIV, and Long Term HealthR01MH100470 · NIMH · KING'S COLLEGE LONDON · PI FAIRALL, LARA ROSEMARY, PETERSEN, INGE · 2013 to 2018
$2.0M
CSRD VA 1Department for International Development 0Department for International Development 2Department for International Development 4Department for International Development 6Department of HealthGlobal Health 136Global Health 16Global Health 54Health ResearchKing's College LondonMedical Research Council MR/R023697/1Medical Research Council MR/S001255/1National Institute for Health ResearchNIAID NIH HHS UM1 AI069422NIH HHS 1NIH HHS R01MH100470NIH HHS R023697NIH HHS S001255NIMH NIH HHS R01 MH100470South African Medical Research Council
6 · The paper itself

Abstract

objectiveTo describe the receipt of a diagnosis, referral and treatment for depression in people receiving antiretroviral therapy (ART), with depressive symptoms and attending primary care clinics in South Africa, and investigate factors associated with receiving these components of care.

methodsThis is a secondary analysis of data from a randomised controlled trial of an intervention intended to improve detection and treatment of depression in primary care patients receiving ART. In this analysis, we combined cross-sectional and longitudinal data from the intervention and control arms. Using regression models and adjusting for intra-cluster correlation of outcomes, we investigated associations between socioeconomic characteristics, depressive symptoms, stress, disability and stigma, and receipt of a diagnosis, referral and treatment for depression.

resultsOf 2002 participants enrolled, 18% reported a previous diagnosis of depression by a healthcare worker and 10% reported having received counselling from a specialist mental health worker. Diagnosis, referral and counselling during the follow-up period were appropriately targeted, being independently more frequent in participants with higher enrolment scores for depressive symptoms, stress or disability. Participants with higher stigma scores at enrolment were independently less likely to receive counselling. Severe socio-economic deprivation was common but was not associated with treatment.

conclusionWhile the receipt of a diagnosis, referral and treatment for depression were uncommon, they seemed to be appropriately targeted. Socio-economic deprivation was not associated with treatment.

Indexed as

Primary Health CareReferral and ConsultationAdultAntirheumatic AgentsCounselingCross-Sectional StudiesDepressionFemaleHIV InfectionsHumansLogistic ModelsMaleMiddle AgedPovertySocial StigmaSouth AfricaAntirheumatic Agentsantiretroviral therapydepression diagnosisdepression treatmentdisabilitymultimorbiditystigma

Identifiers

PMID32985080
PMCPMC7756779
OpenAlexW3087908728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.