ArticleBJOG : an international journal of obstetrics and gynaecology2021
Parity-related variation in cortisol concentrations in hair during pregnancy.
Article in BJOG : an international journal of obstetrics and gynaecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Mapping of Determinants of Urinary Sex Steroid Metabolites During Late Pregnancy: Results from Two Spanish Cohorts.International journal of molecular sciences · 2025Article
- Physiological and Perceived Stress, Anxiety, Depression and Burnout Among ICU Staff During the COVID-19 Pandemic in Sweden-An Observational Study.Acta anaesthesiologica Scandinavica · 2025Observational
- The effect of cortisol in early pregnancy on postpartum depressive symptoms.Scientific reports · 2025Article
- Hair cortisol concentrations in pregnant women with bipolar, depressive, or schizophrenic spectrum disorders.Archives of women's mental health · 2024Article
- Time-course changes in fingernail cortisol levels during pregnancy and postpartum.Scientific reports · 2024Article
- Childbirth-related posttraumatic stress symptoms - examining associations with hair endocannabinoid concentrations during pregnancy and lifetime trauma.Translational psychiatry · 2023Article
- Prenatal stress, anxiety and depression alter transcripts, proteins and pathways associated with immune responses at the maternal-fetal interface†.Biology of reproduction · 2022Article
- Breastfeeding and cortisol in hair in children.International breastfeeding journal · 2021Article
- Parity-related variation in cortisol concentrations in hair during pregnancy.BJOG : an international journal of obstetrics and gynaecology · 2021Article
- Residential exposure to air pollution and access to neighborhood greenspace in relation to hair cortisol concentrations during the second and third trimester of pregnancy.Environmental health : a global access science source · 2021Article
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5 authors.
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Abstract
objectiveTo investigate hair cortisol concentrations (HCC) monthly in pregnant women and to explore the effect of parity.
designProspective cohort study from gestational week (GW) 26, at childbirth and postpartum.
settingAn antenatal care clinic in southeast Sweden. SAMPLE: 390 pregnant women.
methodsCortisol was measured using radioimmunoassay in methanol extracts of ground hair samples.
main outcome measuresHair cortisol concentrations.
resultsBoth primi- and multiparae exhibited an increase in HCC throughout pregnancy. Primiparae had significantly higher HCC in the latter part of the last trimester compared with multiparae (1 month P = 0.003, 2 months P = 0.038). The use of psychotropic medication in the first trimester correlated to HCC postpartum (P < 0.001). HCC in GW 14-17 was associated with HCC in GW 18-21 (primiparae and multiparae, P < 0.001), GW 22-25 (primiparae P = 0.036, multiparae P = 0.033), and 2 months postpartum (primiparae P = 0.049). HCC in GW 18-21 was associated with GW 22-25 in both primiparae (P < 0.001) and multiparae (P < 0.001) as well as 2 months prior to childbirth among primiparae (<0.037). In general, all estimates of HCC in pregnancy and postpartum showed a significant association between HCC for a specific month and the HCC in the previous month (all P < 0.001), except for the association of HCC among primiparae in GW 22-25 and 3 months prior to childbirth.
conclusionsIncreased cortisol concentrations in hair were observed during pregnancy, which decreased 3 months prior to childbirth in multiparae. The results indicate a quicker suppression of the hypothalamic CRH (corticotropin-releasing hormone) production by placenta CRH in multiparous women. TWEETABLE ABSTRACT: Multiparae have a quicker suppression of hypothalamic CRH production by placenta CRH during pregnancy compared to primiparae.
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