Evidence map›Paper›PMID 32984987›Full record

ArticleDrug development research2021

Superiority of cilostazol among antiplatelet FDA-approved drugs against COVID 19 M

Mohammed A Abosheasha, Afnan H El-Gowily

Abstract read
In one paragraph

Article in Drug development research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
  6. Review
  7. Article
  8. Novel Drug Design for Treatment of COVID-19: A Systematic Review of Preclinical Studies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Review
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mohammed A AbosheashaCellular Genetics Laboratory, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.ORCID 0000-0002-8866-0040
Afnan H El-GowilyDepartment of Chemistry, Biochemistry Division, Faculty of Science, Tanta University, Tanta, Egypt.ORCID 0000-0001-5290-7278

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID 19) was first identified in Wuhan, China near the end of 2019. To date, COVID-19 had spread to almost 235 countries and territories due to its highly infectious nature. Moreover, there is no vaccine or Food and Drug Administration (FDA)-approved drug. More time is needed to establish one of them. Consequently, the drug repurposing approach seems to be the most attractive and quick solution to accommodate this crisis. In this regard, we performed molecular docking-based virtual screening of antiplatelet FDA-approved drugs on the key two viral target proteins: main protease (M

Indexed as

COVID-19 Drug TreatmentCilostazolCoronavirus 3C ProteasesDrug ApprovalDrug Evaluation, PreclinicalDrug RepositioningEicosapentaenoic AcidEpoprostenolHumansIloprostMolecular Docking SimulationPlatelet Aggregation InhibitorsPrasugrel HydrochlorideSARS-CoV-2Spike Glycoprotein, CoronavirusUnited StatesCilostazolCoronavirus 3C ProteasesEicosapentaenoic Acideicosapentaenoic acid ethyl esterEpoprostenolIloprostPlatelet Aggregation InhibitorsPrasugrel HydrochlorideSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antiplateletCOVID-19molecular dockingMproSARS-CoV-2spike glycoprotein

Identifiers

PMID32984987
PMCPMC7646641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.