Evidence map›Paper›PMID 32984567›Full record

ArticleHeliyon2020

A SARS-CoV-2 host infection model network based on genomic human Transcription Factors (TFs) depletion.

Massimiliano Chetta, Alessandra Rosati, Liberato Marzullo, Marina Tarsitano, Nenad Bukvic

Abstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Massimiliano ChettaOspedale Antonio Cardarelli, O.C. di Genetica Medica e di Laboratorio, A.O.R.N. Cardarelli, Medical Genetics Laboratory, Building Y, Naples, Italy.
Alessandra RosatiDepartment of Medicine, Surgery and Dentistry "Schola Medica Salernitana", University of Salerno, Baronissi, 84081, Italy.
Liberato MarzulloDepartment of Medicine, Surgery and Dentistry "Schola Medica Salernitana", University of Salerno, Baronissi, 84081, Italy.
Marina TarsitanoOspedale Antonio Cardarelli, O.C. di Genetica Medica e di Laboratorio, A.O.R.N. Cardarelli, Medical Genetics Laboratory, Building Y, Naples, Italy.
Nenad BukvicAzienda Ospedaliero Universitaria Consorziale Policlinico di Bari, Piazza Giulio Cesare 11, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In December 2019 a new beta-coronavirus was isolated and characterized by sequencing samples from pneumonia patients in Wuhan, Hubei Province, China. Coronaviruses are positive-sense RNA viruses widely distributed among different animal species and humans in which they cause respiratory, enteric, liver and neurological symptomatology. Six species of coronavirus have been described (HCoV-229E, HCoV-OC43, HCoV-NL63 and HCoV-HKU1) that cause cold-like symptoms in immunocompetent or immunocompromised subjects and two strains of sometimes fatal zoonotic origin that cause severe acute respiratory syndrome (SARS-CoV and MERS-CoV). The SARS-CoV-2 strain is the emerging seventh member of the coronavirus family, which is actually determining a global emergency.

Indexed as

BioinformaticsGeneticsHaploinsufficiencyInfectious diseaseInteractions within host genomeSARS-CoV-2 strainTranscriptional factors depletionVirology

Identifiers

PMID32984567
PMCPMC7501776

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.