Evidence map›Paper›PMID 32984403›Full record

ReviewFrontiers in molecular biosciences2020

New Insights on the Role of

Georgia Dermentzaki, Francesco Lotti

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. N6-methyladenosine and Neurological Diseases.Molecular neurobiology · 2022
    Review
  14. Review
  15. RNA Modifications and RNA Metabolism in Neurological Disease Pathogenesis.International journal of molecular sciences · 2021
    Review
  16. Review
  17. Article
  18. Emerging Role of mFrontiers in cell and developmental biology · 2021
    Review
  19. NFrontiers in cell and developmental biology · 2021
    Article
  20. Long Non-coding RNAs in Pathogenesis of Neurodegenerative Diseases.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Georgia DermentzakiCenter for Motor Neuron Biology and Disease, Department of Pathology and Cell Biology, Columbia University, New York City, NY, United States.
Francesco LottiCenter for Motor Neuron Biology and Disease, Department of Pathology and Cell Biology, Columbia University, New York City, NY, United States.
Columbia University · US

Funding

METTL3-mediated regulation of motor neuron functionR01AG084965 · NIA · HUNTER COLLEGE · PI Francesco Lotti · 2023 to 2026
$1.1M
SMN post-translational modification in Spinal Muscular AtrophyR21NS101575 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOTTI, FRANCESCO · 2017 to 2018
$440k
NIA NIH HHS R01 AG084965NINDS NIH HHS R21 NS101575
6 · The paper itself

Abstract

RNA modifications termed epitranscriptomics represent an additional layer of gene regulation similar to epigenetic mechanisms operating on DNA. The dynamic nature and the increasing number of RNA modifications offer new opportunities for a rapid fine-tuning of gene expression in response to specific environmental cues. In cooperation with a diverse and versatile set of effector proteins that "recognize" them, these RNA modifications have the ability to mediate and control diverse fundamental cellular functions, such as pre-mRNA splicing, nuclear export, stability, and translation.

Indexed as

m6Amood disordersN6-methyladenosineneurodegenerative disordersneurodevelopmentneurodevelopmental disordersRNA metabolismRNA modifications

Identifiers

PMID32984403
PMCPMC7492240
OpenAlexW3082903791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.