Evidence map›Paper›PMID 32984353›Full record

ArticleFrontiers in cell and developmental biology2020

Molecular Mechanism Underlying the Action of

Melanie Balbach, Hussein Hamzeh, Jan F Jikeli, Christoph Brenker, Christian Schiffer, Jan N Hansen, Pia Neugebauer, Christian Trötschel, Luca Jovine, Ling Han and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Cryo-EM structure of human NaNature communications · 2026
    Article
  2. Article
  3. Soluble adenylyl cyclase in nonmammalian sperm is directly controlled by pH, not by HCOProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Female fertility and the mammalian egg'sHistology and histopathology · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. NaInternational journal of molecular sciences · 2023
    Review
  10. Article
  11. Review
  12. The SLC9C2 Gene Product (NaInternational journal of molecular sciences · 2023
    Article
  13. Article
  14. Article
  15. CatSper and its CaM-like CaFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  16. Review
  17. Article
  18. Starvation induces an increase in intracellular calcium and potentiates the progesterone-induced mouse sperm acrosome reaction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Melanie BalbachCenter of Advanced European Studies and Research, Department of Molecular Sensory Systems, Bonn, Germany.
Hussein HamzehCenter of Advanced European Studies and Research, Department of Molecular Sensory Systems, Bonn, Germany.
Jan F JikeliInstitute of Innate Immunity, Department of Biophysical Imaging, Medical Faculty, University of Bonn, Bonn, Germany.
Christoph BrenkerCenter of Reproductive Medicine and Andrology, University Hospital Münster, University of Münster, Münster, Germany.
Christian SchifferCenter of Reproductive Medicine and Andrology, University Hospital Münster, University of Münster, Münster, Germany.
Jan N HansenInstitute of Innate Immunity, Department of Biophysical Imaging, Medical Faculty, University of Bonn, Bonn, Germany.
Pia NeugebauerInstitute of Innate Immunity, Department of Biophysical Imaging, Medical Faculty, University of Bonn, Bonn, Germany.
Christian TrötschelBiochemie der Pflanzen, Ruhr-Universität Bochum, Bochum, Germany.
Luca JovineDepartment of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden.
Ling HanDepartment of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden.
Harvey M FlormanDepartment of Obstetrics and Gynecology, University of Massachusetts Medical School Worcester, Worcester, MA, United States.
U Benjamin KauppCenter of Advanced European Studies and Research, Department of Molecular Sensory Systems, Bonn, Germany.
Timo StrünkerCenter of Reproductive Medicine and Andrology, University Hospital Münster, University of Münster, Münster, Germany.
Dagmar WachtenInstitute of Innate Immunity, Department of Biophysical Imaging, Medical Faculty, University of Bonn, Bonn, Germany.
University of Bonn · DECenter of Advanced European Studies and Research · DEKarolinska Institutet · SEUniversity Hospital Münster · DERuhr University Bochum · DEUniversity of Massachusetts Chan Medical School · USUniversity of Münster · DE

Funding

Regulators of the sperm acrosome reactionR01HD046948 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FLORMAN, HARVEY M · 2004 to 2014
$3.2M
NICHD NIH HHS R01 HD046948
6 · The paper itself

Abstract

Mammalian oocytes are enveloped by the zona pellucida (ZP), an extracellular matrix of glycoproteins. In sperm, stimulation with ZP proteins evokes a rapid Ca

Indexed as

calciummouse spermsodium-proton exchangesperm motilityzona pellucida

Identifiers

PMID32984353
PMCPMC7487327
OpenAlexW3081979328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.