Evidence map›Paper›PMID 32984350›Full record

ArticleFrontiers in cell and developmental biology2020

Impact of Sustained Transforming Growth Factor-β Receptor Inhibition on Chromatin Accessibility and Gene Expression in Cultured Human Endometrial MSC.

Raffaella Lucciola, Pavle Vrljicak, Shanti Gurung, Caitlin Filby, Saeedeh Darzi, Joanne Muter, Sascha Ott, Jan J Brosens, Caroline E Gargett

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Establishing 3D Endometrial Organoids from the Mouse Uterus.Journal of visualized experiments : JoVE · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Endometrial SUSD2Journal of personalized medicine · 2021
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Raffaella LucciolaThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Pavle VrljicakDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Shanti GurungThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Caitlin FilbyThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Saeedeh DarziThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Joanne MuterDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Sascha OttDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Jan J BrosensDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Caroline E GargettThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Hudson Institute of Medical Research · AUUniversity Hospitals Coventry and Warwickshire NHS Trust · GBMonash University · AUUniversity of Warwick · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Endometrial mesenchymal stem cells (eMSC) drive the extraordinary regenerative capacity of the human endometrium. Clinical application of eMSC for therapeutic purposes is hampered by spontaneous differentiation and cellular senescence upon large-scale expansion

Indexed as

chromatinendometriumgene regulatory networkshumanmesenchymal stem cellretinoic acid receptor betatransforming growth factor receptor beta

Identifiers

PMID32984350
PMCPMC7490520
OpenAlexW3082290803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.