Evidence map›Paper›PMID 32984348›Full record

ArticleFrontiers in cell and developmental biology2020

Pak1ip1 Loss-of-Function Leads to Cell Cycle Arrest, Loss of Neural Crest Cells, and Craniofacial Abnormalities.

Alexios A Panoutsopoulos, Angelo Harlan De Crescenzo, Albert Lee, Amelia MacKenzie Lu, Adam P Ross, Laura N Borodinsky, Ralph Marcucio, Paul A Trainor, Konstantinos S Zarbalis

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. RNA Polymerases I and III in development and disease.Seminars in cell & developmental biology · 2023
    Review
  3. Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Alexios A PanoutsopoulosDepartment of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Davis, CA, United States.
Angelo Harlan De CrescenzoDepartment of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Davis, CA, United States.
Albert LeeDepartment of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Davis, CA, United States.
Amelia MacKenzie LuDavid B. Falk College of Sport and Human Dynamics - Department of Public Health, Syracuse University, Syracuse, NY, United States.
Adam P RossDepartment of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Davis, CA, United States.
Laura N BorodinskyInstitute for Pediatric Regenerative Medicine, Shriners Hospitals for Children - Northern California, Sacramento, CA, United States.
Ralph MarcucioDepartment of Orthopedic Surgery, School of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Paul A TrainorStowers Institute for Medical Research, Kansas City, MO, United States.
Konstantinos S ZarbalisDepartment of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Davis, CA, United States.
Shriners Hospitals for Children - Northern California · USUniversity of California, Davis · USStowers Institute for Medical Research · USSyracuse University · USUniversity of California, San Francisco · US

Funding

Craniofacial Defects in the Manta-Ray Line: A Novel Model for RibosomopathiesR01DE022830 · NIDCR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZARBALIS, KONSTANTINOS · 2015 to 2018
$1.5M
NIDCR NIH HHS R01 DE022830
6 · The paper itself

Abstract

Neural crest cells (NCCs) comprise a transient progenitor cell population of neuroepithelial origin that contributes to a variety of cell types throughout vertebrate embryos including most mesenchymal cells of the cranial and facial structures. Consequently, abnormal NCC development underlies a variety of craniofacial defects including orofacial clefts, which constitute some of the most common birth defects. We previously reported the generation of

Indexed as

developmentmouseneural crestorofacial cleftsPak1ip1ribosomopathies

Identifiers

PMID32984348
PMCPMC7490522
OpenAlexW3082938243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.