Evidence map›Paper›PMID 32984059›Full record

ArticleFrontiers in oncology2020

Dysregulated Phosphorylation of p53, Autophagy and Stemness Attributes the Mutant p53 Harboring Colon Cancer Cells Impaired Sensitivity to Oxaliplatin.

Lubna Therachiyil, Javeria Haroon, Fairooz Sahir, Kodappully S Siveen, Shahab Uddin, Michal Kulinski, Joerg Buddenkotte, Martin Steinhoff, Roopesh Krishnankutty

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. The Red AlgaCurrent issues in molecular biology · 2026
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  4. Molecules (Basel, Switzerland) · 2026
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  5. NovelCancer drug resistance (Alhambra, Calif.) · 2026
    Article
  6. Tetraarsenic Hexoxide Enhanced the Anticancer Effects ofInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. MiRZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. TRIM29 Reverses Oxaliplatin Resistance of P53 Mutant Colon Cancer Cell.Canadian journal of gastroenterology & hepatology · 2021
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Lubna TherachiyilTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Javeria HaroonTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Fairooz SahirTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Kodappully S SiveenTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Shahab UddinTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Michal KulinskiTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Joerg BuddenkotteTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Martin SteinhoffTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Roopesh KrishnankuttyTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Hamad Medical Corporation · QACornell University · USQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) forms one of the highest ranked cancer types in the world with its increasing incidence and mortality rates despite the advancement in cancer therapeutics. About 50% of human CRCs are reported to have defective p53 expression resultant of

Indexed as

autophagycolon cancerdrug resistanceHCT 116HT 29oxaliplatinp53therapy

Identifiers

PMID32984059
PMCPMC7485421
OpenAlexW3081883217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.