Evidence map›Paper›PMID 32984049›Full record

ArticleFrontiers in oncology2020

Toxicoproteomics Disclose Pesticides as Downregulators of TNF-α, IL-1β and Estrogen Receptor Pathways in Breast Cancer Women Chronically Exposed.

Luciana Pizzatti, Aedra Carla Bufalo Kawassaki, Bruna Fadel, Fabio C S Nogueira, Joseph A M Evaristo, Nicole Woldmar, Géssica Tuani Teixeira, Janaína Carla Da Silva, Thalita Basso Scandolara, Daniel Rech and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Occupational exposure to pesticides deregulates systemic cortisol levels in women with breast cancer and correlates with poor prognosis features.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Impact of Pesticides on Human Health in the Last Six Years in Brazil.International journal of environmental research and public health · 2022
    Review
  14. Determination of glyphosate in breast milk of lactating women in a rural area from Paraná state, Brazil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Luciana PizzattiFederal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Aedra Carla Bufalo KawassakiState University of West Paraná, UNIOESTE, Paraná, Brazil.
Bruna FadelFederal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Fabio C S NogueiraFederal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Joseph A M EvaristoFederal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Nicole WoldmarFederal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Géssica Tuani TeixeiraState University of West Paraná, UNIOESTE, Paraná, Brazil.
Janaína Carla Da SilvaState University of West Paraná, UNIOESTE, Paraná, Brazil.
Thalita Basso ScandolaraFederal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Daniel RechState University of West Paraná, UNIOESTE, Paraná, Brazil.
Luciano Pessôa Zanetti CandiottoState University of West Paraná, UNIOESTE, Paraná, Brazil.
Guilherme Ferreira SilveiraCarlos Chagas Institute, Curitiba, Brazil.
Wander Rogério PavanelliState University of Londrina, Londrina, Brazil.
Carolina PanisState University of West Paraná, UNIOESTE, Paraná, Brazil.
Universidade Estadual do Oeste do Paraná · BRUniversidade Federal do Rio de Janeiro · BRFundação Carlos Chagas · BRUniversidade Estadual de Londrina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deleterious effects have been widely associated with chronic pesticide exposure, including cancer development. In spite of several known consequences that pesticides can trigger in the human body, few is known regarding its impact on breast cancer women that are chronically exposed to such substances during agricultural work lifelong. In this context, the present study performed a high-throughput toxicoproteomic study in association with a bioinformatics-based design to explore new putative processes and pathways deregulated by chronic pesticide exposure in breast cancer patients. To reach this goal, we analyzed comparatively non-depleted plasma samples from exposed (

Indexed as

breast cancerestrogen signalinginterleukin beta 1toxicoproteomicstumor necrosis factor alfa

Identifiers

PMID32984049
PMCPMC7483484
OpenAlexW3081308761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.