Evidence map›Paper›PMID 32984035›Full record

ArticleFrontiers in oncology2020

Genomic Profiling Identified

Yosuke Hirotsu, Hitoshi Yokoyama, Kenji Amemiya, Takashi Hagimoto, Kyoko Hosaka, Toshio Oyama, Hitoshi Mochizuki, Masao Omata

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Prediction of Postoperative Intravesical Recurrence Using Urine DNA Monitoring in Nonmuscular-Invasive Urothelial Bladder Cancer.International journal of urology : official journal of the Japanese Urological Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yosuke HirotsuGenome Analysis Center, Yamanashi Central Hospital, Kofu, Japan.
Hitoshi YokoyamaDepartment of Urology, Yamanashi Central Hospital, Kofu, Japan.
Kenji AmemiyaGenome Analysis Center, Yamanashi Central Hospital, Kofu, Japan.
Takashi HagimotoDepartment of Urology, Yamanashi Central Hospital, Kofu, Japan.
Kyoko HosakaDepartment of Urology, Yamanashi Central Hospital, Kofu, Japan.
Toshio OyamaDepartment of Pathology, Yamanashi Central Hospital, Kofu, Japan.
Hitoshi MochizukiGenome Analysis Center, Yamanashi Central Hospital, Kofu, Japan.
Masao OmataGenome Analysis Center, Yamanashi Central Hospital, Kofu, Japan.
Yamanashi Prefectural Central Hospital · JPBunkyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic profiling of tumors enables therapeutic decisions, and identifying drug-matched mutations will prolong survival and prognosis. Here, we generated a custom panel for detecting genetic alterations in 19 patients with urothelial bladder cancer. This panel targeted 71 genes associated with urological cancer. Targeted sequencing was performed on formalin-fixed paraffin-embedded tumor tissues. Paired patient-matched tumor and blood samples were subjected to this analysis. A total of 142 somatic mutations were detected in 19 tumor tissues. At least one non-synonymous mutation was detected in all tumor tissues, and

Indexed as

actionable mutationbladder cancerERCC2NGSprecision medicine

Identifiers

PMID32984035
PMCPMC7480179
OpenAlexW3080187737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.