Evidence map›Paper›PMID 32983983›Full record

ArticleFrontiers in oncology2020

Prevalence of Phosphatidylinositol-3-Kinase (PI3K) Pathway Alterations and Co-alteration of Other Molecular Markers in Breast Cancer.

Katia Khoury, Antoinette R Tan, Andrew Elliott, Joanne Xiu, Zoran Gatalica, Arielle L Heeke, Claudine Isaacs, Paula R Pohlmann, Lee S Schwartzberg, Michael Simon and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
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  7. Article
  8. Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  9. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Katia KhouryLombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC, United States.
Antoinette R TanLevine Cancer Institute, Charlotte, NC, United States.
Andrew ElliottCaris Life Sciences, Phoenix, AZ, United States.
Joanne XiuCaris Life Sciences, Phoenix, AZ, United States.
Zoran GatalicaDepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.
Arielle L HeekeLevine Cancer Institute, Charlotte, NC, United States.
Claudine IsaacsLombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC, United States.
Paula R PohlmannLombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC, United States.
Lee S SchwartzbergWest Cancer Center, Memphis, TN, United States.
Michael SimonKarmanos Cancer Institute, Wayne State University, Detroit, MI, United States.
W Michael KornCaris Life Sciences, Phoenix, AZ, United States.
Sandra M SwainLombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC, United States.
Filipa LynceLombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC, United States.
MedStar Georgetown University Hospital · USCaris Life Sciences (United States) · USLevine Cancer Institute · USGeorgetown University · USThe Barbara Ann Karmanos Cancer Institute · USUniversity of Oklahoma Health Sciences Center · USWest Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

breast cancerCDH1molecular profilingPD-L1PI3K inhibitorPIK3CA-AKT1-PTEN pathway

Identifiers

PMID32983983
PMCPMC7489343
OpenAlexW3081940595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.