Evidence map›Paper›PMID 32983763›Full record

ArticlePlastic and reconstructive surgery. Global open2020

Use of the Omental Free Flap for Treatment of Chronic Anterior Skull Base Infections.

George Kokosis, Joshua Vorstenbosch, Arianna Lombardi, Meghana G Shamsunder, Babak Mehrara, Geoffrey E Hespe, Laura Wang, Cameron W Brennan, Ian Ganly, Evan Matros

Open access · goldAbstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

George KokosisDivision of Plastic and Reconstructive Surgery, Memorial Sloan Kettering, New York, N.Y.
Joshua VorstenboschDivision of Plastic and Reconstructive Surgery, Memorial Sloan Kettering, New York, N.Y.
Arianna LombardiDivision of Plastic and Reconstructive Surgery, Memorial Sloan Kettering, New York, N.Y.
Meghana G ShamsunderDivision of Plastic and Reconstructive Surgery, Memorial Sloan Kettering, New York, N.Y.
Babak MehraraDivision of Plastic and Reconstructive Surgery, Memorial Sloan Kettering, New York, N.Y.
Geoffrey E HespeDivision of Plastic and Reconstructive Surgery, University of Michigan, Ann Arbor, Mich.
Laura WangDivision of Plastic and Reconstructive Surgery, Memorial Sloan Kettering, New York, N.Y.
Cameron W BrennanDepartment of Neurosurgery, Memorial Sloan Kettering, New York, N.Y.
Ian GanlyDivision of Head and Neck Surgery, Memorial Sloan Kettering, New York, N.Y.
Evan MatrosDivision of Plastic and Reconstructive Surgery, Memorial Sloan Kettering, New York, N.Y.
Memorial Sloan Kettering Cancer Center · USUniversity of Michigan · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Chronic complications following anterior cranial fossa tumor extirpation, such as cerebrospinal fluid leak, meningitis, mucocele, pneumocephalus, and abscess, negatively impact patient quality of life. Robust vascularized tissue is generally required to adequately reconstruct and obliterate this complex geometric space. The aim of this study was to describe outcomes and advantages of the omental flap for these defects. Following institutional review board approval, a prospective, reconstructive database was reviewed from 2011 to 2020. Four patients with chronic anterior skull base complications treated with omental flap reconstruction were identified, with chart reviews performed. Median time from the index operation until the complication ultimately required a free omental transfer was 7.3 years. All patients underwent adjuvant radiation with the indications for surgery, including cerebral abscess, recurrent meningitis, osteomyelitis, and pneumocephalus. All free flaps survived without any need for revision. There were no donor site complications. One patient had delayed healing at an adjacent nasal wound that healed secondarily. At a median follow-up of 19.4 months, none of the patients had recurrent infections. The omental free flap has a number of properties, which make it ideally suitable for anterior skull base defects. Its malleable nature combined with the presence of multiple vascular arcades enable flexibility in flap design to contour to the crevices of 3-dimensional skull base defects. Although other free flaps are available to the plastic surgeon, the versatility and reliability of the omentum make it a first-line consideration for anterior skull base reconstruction.

Identifiers

PMID32983763
PMCPMC7489647
OpenAlexW3087890432

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.