Evidence map›Paper›PMID 32983551›Full record

ArticleBMC nutrition2020

A comparison of a ketogenic diet with a LowGI/nutrigenetic diet over 6 months for weight loss and 18-month follow-up.

Maria Vranceanu, Craig Pickering, Lorena Filip, Ioana Ecaterina Pralea, Senthil Sundaram, Aseel Al-Saleh, Daniela-Saveta Popa, Keith A Grimaldi

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04330209 completednot on this map

Comparing a Low-GI Nutrigenetic and Ketogenic Diet for Weight Loss With 18 Month Follow-up

TypeobservationalSponsorIuliu Hatieganu University of Medicine and PharmacyRan2014 to 2017Enrolled114ConditionsWeight Loss, Glucose, High Blood, LDL Hyperlipoproteinemia, HDLArmsweight loss diets
NCT05562440 nacompletednot on this mapstarted 2022, after this paper: background citation

The Perspective of Healthy Individuals on Breast Cancer Risk Prediction Report in The Indonesian Population (Perspektif Para Individu Sehat Terhadap Laporan Prediksi Risiko Kanker Payudara)

TypeinterventionalSponsorNalagenetics Pte LtdRan2022 to 2023Enrolled10ConditionsBreast CancerArmsFocus Group Discussion
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Adherence to Behavioral Weight Management: A Scoping Review of Definitions, Measurement, and Components.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Maria VranceanuDepartment of Toxicology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania.
Craig PickeringInstitute of Coaching and Performance, School of Sport and Wellbeing, University of Central Lancashire, Preston, UK.
Lorena FilipDepartment of Bromatology and Hygiene, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania.
Ioana Ecaterina PraleaDepartment of Toxicology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania.
Senthil SundaramPrenetics Ltd, Quarry Bay, Hong Kong SAR China.
Aseel Al-SalehArab Gulf University, Manama, Bahrain.
Daniela-Saveta PopaDepartment of Toxicology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania.
Keith A GrimaldiDepartment of Nutrigenetics and Personalized Nutrition, Eurogenetica, Rome, Italy.ORCID 0000-0003-2271-5990
Iuliu Hațieganu University of Medicine and Pharmacy · ROArabian Gulf University · BHPrenetics (China) · CNUniversity of Lancashire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity and its related metabolic disturbances represent a huge health burden on society. Many different weight loss interventions have been trialled with mixed efficacy, as demonstrated by the large number of individuals who regain weight upon completion of such interventions. There is evidence that the provision of genetic information may enhance long-term weight loss, either by increasing dietary adherence or through underlying biological mechanisms.

methodsThe investigators followed 114 overweight and obese subjects from a weight loss clinic in a 2-stage process. 1) A 24-week dietary intervention. The subjects self-selected whether to follow a standardized ketogenic diet (

resultsAfter 24 weeks, the keto group lost more weight: - 26.2 ± 3.1 kg vs - 23.5 ± 6.4 kg (

conclusionsThese findings demonstrate that the ketogenic group experienced enhanced weight loss during the 24-week dietary intervention. However, at 18-month follow up, the personalised nutrition group (lowGI/NG) lost significantly more weight and experienced significantly greater improvements in measures of cholesterol and blood glucose. This suggests that personalising nutrition has the potential to enhance long-term weight loss and changes in cardiometabolic parameters.

trial registrationNCT04330209, Registered 01/04/2020, retrospectively registered.

Indexed as

BMICholesterolGenetic testingGlycaemic indexKetogenicNutrigeneticsWeight loss

Identifiers

PMID32983551
PMCPMC7513277
OpenAlexW3088150213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.