Evidence map›Paper›PMID 32983550›Full record

ArticleAsthma research and practice2020

Disease control in patients with asthma and respiratory symptoms (wheezing, cough) during sleep.

Jonathan Doenges, Elisabeth Kuckuck, Werner Cassel, Olaf Hildebrandt, Andreas Weissflog, Keywan Sohrabi, Niklas Koehler, Volker Gross, Timm Greulich, Ulrich Koehler

Open access · goldAbstract read
In one paragraph

Article in Asthma research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Cough monitoring systems in adults with chronic respiratory diseases: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Asthma management in the digital age.Frontiers in allergy · 2024
    Review
  6. Review
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jonathan DoengesDepartment of Internal Medicine, Division of Pneumology, Intensive Care and Sleep Medicine, Hospital of the University of Marburg, Baldingerstrasse 1, 35033 Marburg, Germany.ORCID 0000-0001-7749-4246
Elisabeth KuckuckDepartment of Internal Medicine, Division of Pneumology, Intensive Care and Sleep Medicine, Hospital of the University of Marburg, Baldingerstrasse 1, 35033 Marburg, Germany.
Werner CasselDepartment of Internal Medicine, Division of Pneumology, Intensive Care and Sleep Medicine, Hospital of the University of Marburg, Baldingerstrasse 1, 35033 Marburg, Germany.
Olaf HildebrandtDepartment of Internal Medicine, Division of Pneumology, Intensive Care and Sleep Medicine, Hospital of the University of Marburg, Baldingerstrasse 1, 35033 Marburg, Germany.
Andreas WeissflogThora Tech GmbH, Gießen, Germany.
Keywan SohrabiUniversity of Applied Sciences, Faculty of Health Sciences, Gießen, Germany.
Niklas KoehlerUniversity of Applied Sciences, Faculty of Health Sciences, Gießen, Germany.
Volker GrossUniversity of Applied Sciences, Faculty of Health Sciences, Gießen, Germany.
Timm GreulichDepartment of Internal Medicine, Division of Pneumology, Intensive Care and Sleep Medicine, Hospital of the University of Marburg, Baldingerstrasse 1, 35033 Marburg, Germany.
Ulrich KoehlerDepartment of Internal Medicine, Division of Pneumology, Intensive Care and Sleep Medicine, Hospital of the University of Marburg, Baldingerstrasse 1, 35033 Marburg, Germany.
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe

methodsRespiratory symptoms like wheezing and cough were recorded with the LEOSound-Monitor for one night in 55 asthmatic patients in their individual domestic setting. Patients were asked to assess their level of asthma subjectively with the ACT. The study consisted of 37 women and 18 men, with a mean age of 41 years, and a mean BMI of 27 kg/m

results60% of the participants were classed as having controlled, and 40% were classed as having partially- or uncontrolled asthma. During sleep wheezing was found in 8 of the 55 asthma patients (14.5%) and coughing was found in 30 patients (54.5%). The median ACT score in wheezing-patients was 14, while in non-wheezing patients it was 21. Uncontrolled asthma was found in 6 of the 8 wheezing-patients. Coughing versus non-coughing patients did not show a significant difference in the ACT-score (20, 22 respectively).

conclusionWheezing is a sign of uncontrolled asthma. The ACT-score in wheezing patients is worse compared to patients without wheezing. LEOSound proofed to be a useful tool in providing an objective evaluation of respiratory symptoms, like coughing and wheezing. In clinical practice, this may allow an improvement in asthma therapy.

Indexed as

AsthmaAsthma control testCoughLong-term monitoring of respiratory soundsWheezing

Identifiers

PMID32983550
PMCPMC7513478
OpenAlexW3088308397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.