Evidence map›Paper›PMID 32983268›Full record

ArticleBeilstein journal of organic chemistry2020

Naphthalene diimide bis-guanidinio-carbonyl-pyrrole as a pH-switchable threading DNA intercalator.

Poulami Jana, Filip Šupljika, Carsten Schmuck, Ivo Piantanida

Open access · diamondAbstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Poulami JanaInstitute for Organic Chemistry, University of Duisburg-Essen, Universitässtrasse 7, 45141 Essen, Germany.ORCID https://orcid.org/0000-0002-0628-6877
Filip ŠupljikaDivision of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, P. O. Box 180, HR-10002 Zagreb, Croatia.
Carsten SchmuckInstitute for Organic Chemistry, University of Duisburg-Essen, Universitässtrasse 7, 45141 Essen, Germany.
Ivo PiantanidaDivision of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, P. O. Box 180, HR-10002 Zagreb, Croatia.ORCID https://orcid.org/0000-0002-9933-446X
Ruđer Bošković Institute · HRUniversity of Duisburg-Essen · DEUniversity of Zagreb · HRVisva-Bharati University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel naphthalene diimde analogue (NDI) equipped at the imide positions with two guanidinio-carbonyl-pyrrole (GCP) pendant arms interacted significantly stronger with ds-DNA at pH 5 than at pH 7, due to reversible protonation of the GCP arms. This was consequence of a pH-switchable threading intercalation into ds-DNAs only at pH 5, while at neutral conditions (pH 7) NDI-GCP

Indexed as

AFMcircular dichroismDNA/RNA recognitionfluorescenceguanidinio-carbonyl-pyrrolenaphthalene diimide

Identifiers

PMID32983268
PMCPMC7492691
OpenAlexW3080428775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.