Evidence map›Paper›PMID 32983182›Full record

ArticleFrontiers in immunology2020

Tristetraprolin Overexpression in Non-hematopoietic Cells Protects Against Acute Lung Injury in Mice.

Ishita Choudhary, Thao Vo, Chandra S Bathula, Richa Lamichhane, Brandon W Lewis, Jayme Looper, Samithamby Jeyaseelan, Perry J Blackshear, Yogesh Saini, Sonika Patial

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  7. Case report:Frontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ishita ChoudharyDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Thao VoDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Chandra S BathulaDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Richa LamichhaneDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Brandon W LewisDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Jayme LooperVeterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Samithamby JeyaseelanPathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Perry J BlackshearSignal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States.
Yogesh SainiDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Sonika PatialDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Louisiana State University · USNational Institute of Environmental Health Sciences · US

Funding

The role of adipocyte-driven inflammation and leptin pathway in pulmonary viral infections caused by SARS-CoV-2 and influenza A virusesP20GM130555 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI Alexandra Noel · 2019 to 2026
$19.9M
Protein CoreP30GM110760 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI KOUSOULAS, KONSTANTIN G · 2014 to 2018
$5.6M
NIGMS NIH HHS P20 GM130555NIGMS NIH HHS P30 GM110760
6 · The paper itself

Abstract

Tristetraprolin (TTP) is a mRNA binding protein that binds to adenylate-uridylate-rich elements within the 3' untranslated regions of certain transcripts, such as tumor necrosis factor (

Indexed as

Acute Lung InjuryAlveolar Epithelial CellsAnimalsBone Marrow TransplantationBronchoalveolar Lavage FluidChemotaxis, LeukocyteCytokinesEndothelial CellsFemaleFibroblastsLipopolysaccharidesMaleMiceMice, KnockoutNeutrophil InfiltrationNeutrophilsCytokineslipopolysaccharide, Escherichia coli O111 B4LipopolysaccharidesTristetraprolinZfp36 protein, mouseacute lung injuryinflammationneutrophiltristetraprolinZfp36

Identifiers

PMID32983182
PMCPMC7493631
OpenAlexW3082675059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.