ReviewFrontiers in immunology2020
Obesity Accelerates Age Defects in Mouse and Human B Cells.
Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Low-dose tamoxifen ameliorates ovariectomy-induced metabolic and immune dysfunction.GeroScience · 2026Article
- Age but not sex modifies lymphoid immune responses in murine sepsis.Research square · 2026Article
- Cognitive dysfunction in MASLD is linked to platelet activation.Frontiers in neuroscience · 2026Review
- Body condition, age, and sex as modulators of peripheral blood immune-cell populations and lymphocyte proliferation in cats.Frontiers in veterinary science · 2026Article
- Obinutuzumab for refractory minimal change disease in obese patients: a case series.Frontiers in medicine · 2026Article
- The Crosstalk Between B Cells and the Skeletal System During Development, Aging, and in Pathological Conditions.Current osteoporosis reports · 2025Review
- Immunoinflammation and post-translational modifications in the aging process.Journal of translational medicine · 2025Review
- Females with obesity exhibit greater influenza vaccine-induced immunity and protection than males in a mouse model.Frontiers in immunology · 2025Article
- Computational and digital analyses in the INSPIRE mouse cohort to define sex-specific functional determinants of biological aging.Science advances · 2024Article
- Metabolic regulation of the immune system in health and diseases: mechanisms and interventions.Signal transduction and targeted therapy · 2024Review
- Excess of body weight is associated with accelerated T-cell senescence in hospitalized COVID-19 patients.Immunity & ageing : I & A · 2024Article
- Adipose tissue and hematopoiesis: Friend or foe?Journal of clinical laboratory analysis · 2023Review
- COVID-19 mRNA vaccine protects against SARS-CoV-2 Omicron BA.1 infection in diet-induced obese mice through boosting host innate antiviral responses.EBioMedicine · 2023Article
- Identification and Verification of Biomarkers and Immune Infiltration in Obesity-Related Atrial Fibrillation.Biology · 2023Article
- Article
- COVID-19 diverse outcomes: Aggravated reinfection, type I interferons and antibodies.Medical hypotheses · 2022Article
- Rituximab-Induced Hypogammaglobulinemia and Risk of Infection in Neuromyelitis Optica Spectrum Disorders: A 14-Year Real-Life Experience.Neurology(R) neuroimmunology & neuroinflammation · 2022Article
- The Role of B Lymphocyte Subsets in Adipose Tissue Development, Metabolism, and Aging.Comprehensive Physiology · 2022Article
- T and B Cell Composition and Cytokine Producing Capacity Before and After Bariatric Surgery.Frontiers in immunology · 2022Article
- Age and Sex: Impact on adipose tissue metabolism and inflammation.Mechanisms of ageing and development · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Obesity, similar to aging, is associated with chronic low-grade systemic inflammation, known as inflammaging, and represents a significantly higher risk for developing chronic diseases typical of old age. Immune cells are recruited to the obese adipose tissue (AT) by chemotactic molecules secreted by non-immune and immune cells in the AT, both contributing to the release of several pro-inflammatory mediators that fuel local and systemic inflammation, to the refractory response of immune cells to further
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.