Evidence map›Paper›PMID 32983108›Full record

ArticleFrontiers in immunology2020

Single Nucleotide Polymorphism in

Luciana de Brito Vargas, Renata M Dourado, Leonardo M Amorim, Brenda Ho, Verónica Calonga-Solís, Hellen C Issler, Wesley M Marin, Marcia H Beltrame, Maria Luiza Petzl-Erler, Jill A Hollenbach and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  10. High-Resolution Characterization ofFrontiers in immunology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Luciana de Brito VargasPrograma de Pós-Graduação em Genética, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Renata M DouradoPrograma de Pós-Graduação em Genética, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Leonardo M AmorimPrograma de Pós-Graduação em Genética, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Brenda HoDepartment of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
Verónica Calonga-SolísPrograma de Pós-Graduação em Genética, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Hellen C IsslerPrograma de Pós-Graduação em Genética, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Wesley M MarinDepartment of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
Marcia H BeltramePrograma de Pós-Graduação em Genética, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Maria Luiza Petzl-ErlerPrograma de Pós-Graduação em Genética, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Jill A HollenbachDepartment of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
Danillo G AugustoPrograma de Pós-Graduação em Genética, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Universidade Federal do Paraná · BRUniversity of California, San Francisco · US

Funding

KIR association studies in neurological diseasesU19NS095774 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERNANDEZ-VINA, MARCELO, OKSENBERG, JORGE R. · 2015 to 2019
$7.0M
NINDS NIH HHS U19 NS095774
6 · The paper itself

Abstract

Regulation of NK cell activity is mediated through killer-cell immunoglobulin-like receptors (KIR) ability to recognize human leukocyte antigen (HLA) class I molecules as ligands. Interaction of KIR and HLA is implicated in viral infections, autoimmunity, and reproduction and there is growing evidence of the coevolution of these two independently segregating gene families. By leveraging

Indexed as

HaplotypesHLA-C AntigensHumansKiller Cells, NaturalLinkage DisequilibriumPolymorphism, Single NucleotideReceptors, KIR2DL1HLA-C AntigensKIR2DL1 protein, humanReceptors, KIR2DL1coevolutionexpressionKIRlinkage disequilibriumnatural selectionNK cellspopulation genetics

Identifiers

PMID32983108
PMCPMC7478174
OpenAlexW3080125365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.