Evidence map›Paper›PMID 32983069›Full record

ArticleFrontiers in microbiology2020

Acellular Pertussis Vaccines Induce Anti-pertactin Bactericidal Antibodies Which Drives the Emergence of Pertactin-Negative Strains.

Elodie Lesne, Breeze E Cavell, Irene Freire-Martin, Ruby Persaud, Frances Alexander, Stephen Taylor, Mary Matheson, Cécile A C M van Els, Andrew Gorringe

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pertactin deficiency ofHuman vaccines & immunotherapeutics · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. A role for genomics-based studies of Bordetella pertussis adaptation.Current opinion in infectious diseases · 2025
    Review
  14. Article
  15. Pertussis before, during and after Covid-19.EMBO molecular medicine · 2025
    Review
  16. Article
  17. Frontiers in cellular and infection microbiology · 2025
    Article
  18. Article
  19. Pertussis vaccines, epidemiology and evolution.Nature reviews. Microbiology · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Elodie LesnePublic Health England, Porton Down, United Kingdom.
Breeze E CavellPublic Health England, Porton Down, United Kingdom.
Irene Freire-MartinPublic Health England, Porton Down, United Kingdom.
Ruby PersaudPublic Health England, Porton Down, United Kingdom.
Frances AlexanderPublic Health England, Porton Down, United Kingdom.
Stephen TaylorPublic Health England, Porton Down, United Kingdom.
Mary MathesonPublic Health England, Porton Down, United Kingdom.
Cécile A C M van ElsCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Andrew GorringePublic Health England, Porton Down, United Kingdom.
Public Health England · GBNational Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite high vaccination coverage,

Indexed as

antibodiesantigensbactericidal activityBordetella pertussiscomplementpertactinvaccine

Identifiers

PMID32983069
PMCPMC7481377
OpenAlexW3081811608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.