Evidence map›Paper›PMID 32983046›Full record

ArticleFrontiers in microbiology2020

Phylogeographical Analysis Reveals the Historic Origin, Emergence, and Evolutionary Dynamics of Methicillin-Resistant

Mohamed M H Abdelbary, Edward J Feil, Laurence Senn, Christiane Petignat, Guy Prod'hom, Jacques Schrenzel, Patrice François, Guido Werner, Franziska Layer, Birgit Strommenger and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Deep clustering of bacterial tree images.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  8. Comparative genomics study ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 6 countries.

Mohamed M H AbdelbaryService of Hospital Preventive Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Edward J FeilThe Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom.
Laurence SennService of Hospital Preventive Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Christiane PetignatService of Hospital Preventive Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Guy Prod'homInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Jacques SchrenzelBacteriology Laboratory, Division of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Patrice FrançoisBacteriology Laboratory, Division of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Guido WernerNational Reference Centre for Staphylococci and Enterococci, Division of Nosocomial Pathogens and Antibiotic Resistances, Department of Infectious Diseases, Robert Koch Institute, Wernigerode, Germany.
Franziska LayerNational Reference Centre for Staphylococci and Enterococci, Division of Nosocomial Pathogens and Antibiotic Resistances, Department of Infectious Diseases, Robert Koch Institute, Wernigerode, Germany.
Birgit StrommengerNational Reference Centre for Staphylococci and Enterococci, Division of Nosocomial Pathogens and Antibiotic Resistances, Department of Infectious Diseases, Robert Koch Institute, Wernigerode, Germany.
Annalisa PantostiDepartment of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
Monica MonacoDepartment of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
Olivier DenisNational Reference Centre-Staphylococcus aureus, Department of Microbiology, Hôpital Erasme, Université libre de Bruxelles, Brussels, Belgium.
Ariane DeplanoNational Reference Centre-Staphylococcus aureus, Department of Microbiology, Hôpital Erasme, Université libre de Bruxelles, Brussels, Belgium.
Hajo GrundmannDepartment of Infectious Diseases Epidemiology, The University of Groningen, Groningen, Netherlands.
Dominique S BlancService of Hospital Preventive Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
University of Lausanne · CHRobert Koch Institute · DEIstituto Superiore di Sanità · ITUniversity Hospital of Geneva · CHErasmus Hospital · BERWTH Aachen University · DEUniversité Libre de Bruxelles · BEUniversity of Bath · GBUniversity of Groningen · NL

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundMethicillin-resistant MATERIALS AND

methodsWe aimed to understand the phylogeographic and demographic dynamics of MRSA ST228/ST111 by sequencing 530 representative isolates of this clone that were collected from 14 European countries between 1997 and 2012.

resultsThe phylogenetic analysis revealed distinct lineages of ST228 isolates associated with specific geographic origins. In contrast, isolates of ST111, which is a single locus variant of ST228 sharing the same

conclusionOur results reveal the radiation of distinct lineages of MRSA ST228 from a German progenitor, as the clone spread into different European countries. In Switzerland, ST228 was introduced first in Geneva and was subsequently introduced into Lausanne.

Indexed as

epidemiologygenomic epidemiologyMRSAphylogenyphylogeographyST228WGS

Identifiers

PMID32983046
PMCPMC7479193
OpenAlexW3080244705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.