Evidence map›Paper›PMID 32982991›Full record

ReviewFrontiers in endocrinology2020

Hypertriglyceridemia-Causes, Significance, and Approaches to Therapy.

Leinys S Santos-Baez, Henry N Ginsberg

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  7. Article
  8. Acute pancreatitis caused by severe hypertriglyceridemia in a 61-year-old man on a carnivore diet.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Hypertriglyceridemia Therapy: Past, Present and Future Perspectives.International journal of molecular sciences · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Leinys S Santos-BaezDepartment of Medicine, Division of Preventive Medicine and Nutrition, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Henry N GinsbergDepartment of Medicine, Division of Preventive Medicine and Nutrition, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States.

Funding

POSTDOCTORAL TRAINING IN ARTERIOSCLEROSIS RESEARCHT32HL007343 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENRY N GINSBERG, Muredach P Reilly · 1985 to 2026
$12.7M
Phenotyping Genetic Disorders of Hepatic Lipid and Lipoprotein Metabolism in Cells, Mice, and MenR35HL135833 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2017 to 2023
$6.7M
NHLBI NIH HHS R35 HL135833NHLBI NIH HHS T32 HL007343
6 · The paper itself

Abstract

Hypertriglyceridemia (HTG) is a common metabolic disorder with both genetic and lifestyle factors playing significant roles in its pathophysiology. HTG poses a risk for the development of cardiovascular disease (CVD) in the population at large and for pancreatitis in about two percent of individuals with extremely high levels of triglycerides (TG). This manuscript summarizes the mechanisms underlying the development of HTG as well as its management, including emerging therapies targeted at specific molecular pathways.

Indexed as

Genetic Predisposition to DiseaseDisease ManagementHumansHypertriglyceridemiaTriglyceridesTriglyceridesapolipoproteinBchylomicronshypertriglyceridemialipidslipoproteinsnovel therapeuticstriglyceridesvery low density lipoproteins

Identifiers

PMID32982991
PMCPMC7492386

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.