Evidence map›Paper›PMID 32982916›Full record

ReviewFrontiers in neurology2020

Intensive Care Admission and Early Neuro-Rehabilitation. Lessons for COVID-19?

Alessandro Pincherle, Jane Jöhr, Lisa Pancini, Letizia Leocani, Laura Dalla Vecchia, Philippe Ryvlin, Nicholas D Schiff, Karin Diserens

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Providing rehabilitation to patients recovering from COVID-19: A scoping review.PM & R : the journal of injury, function, and rehabilitation · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. COVID-19: Short and Long-Term Effects of Hospitalization on Muscular Weakness in the Elderly.International journal of environmental research and public health · 2020
    Review
  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Alessandro PincherleAcute Neuro-Rehabilitation Unit and Neurology Unit, Department of Clinical Neurosciences, Lausanne University Hospital-CHUV, Lausanne, Switzerland.
Jane JöhrAcute Neuro-Rehabilitation Unit and Neurology Unit, Department of Clinical Neurosciences, Lausanne University Hospital-CHUV, Lausanne, Switzerland.
Lisa PanciniDepartments of Cardiac and Pulmonary Rehabilitation, IRCSS Istituto Clinico Scientifico Maugeri, Milan, Italy.
Letizia LeocaniDepartment of Neuro-Rehabilitation, Hospital San Raffaele, University Vita Salute, Milan, Italy.
Laura Dalla VecchiaDepartments of Cardiac and Pulmonary Rehabilitation, IRCSS Istituto Clinico Scientifico Maugeri, Milan, Italy.
Philippe RyvlinAcute Neuro-Rehabilitation Unit and Neurology Unit, Department of Clinical Neurosciences, Lausanne University Hospital-CHUV, Lausanne, Switzerland.
Nicholas D SchiffFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, United States.
Karin DiserensAcute Neuro-Rehabilitation Unit and Neurology Unit, Department of Clinical Neurosciences, Lausanne University Hospital-CHUV, Lausanne, Switzerland.
Istituti Clinici Scientifici Maugeri · ITUniversity Hospital of Lausanne · CHVita-Salute San Raffaele University · ITWeill Cornell Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) requires admission to intensive care (ICU) for the management of acute respiratory distress syndrome in about 5% of cases. Although our understanding of COVID-19 is still incomplete, a growing body of evidence is indicating potential direct deleterious effects on the central and peripheral nervous systems. Indeed, complex and long-lasting physical, cognitive, and functional impairments have often been observed after COVID-19. Early (defined as during and immediately after ICU discharge) rehabilitative interventions are fundamental for reducing the neurological burden of a disease that already heavily affects lung function with pulmonary fibrosis as a possible long-term consequence. In addition, ameliorating neuromuscular weakness with early rehabilitation would improve the efficiency of respiratory function as respiratory muscle atrophy worsens lung capacity. This review briefly summarizes the polymorphic burden of COVID-19 and addresses possible early interventions that could minimize the neurological and systemic impact. In fact, the benefits of early multidisciplinary rehabilitation after an ICU stay have been shown to be advantageous in several clinical conditions making an early rehabilitative approach generalizable and desirable to physicians from a wide range of different specialties.

Indexed as

COVID-19early rehabilitationICUimmobilizationmechanical ventilationneurological complications

Identifiers

PMID32982916
PMCPMC7477378
OpenAlexW3080164970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.