Evidence map›Paper›PMID 32982525›Full record

ArticleLung Cancer (Auckland, N.Z.)2020

Favorable Immune Microenvironment in Patients with EGFR and MAPK Co-Mutations.

Wang Yang, Naifei Chen, Lingyu Li, Xiao Chen, Xiangliang Liu, Yongfei Zhang, Jiuwei Cui

Abstract read
In one paragraph

Article in Lung Cancer (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Recent Advances in the Use ofPharmaceutics · 2025
    Review
  3. Review
  4. Review
  5. Overcoming EGFR-TKI resistance by targeting the tumor microenvironment.Chinese medical journal pulmonary and critical care medicine · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wang YangThe Cancer Center of the First Hospital of Jilin University, Changchun, Jilin 130021, People's Republic of China.
Naifei ChenThe Cancer Center of the First Hospital of Jilin University, Changchun, Jilin 130021, People's Republic of China.
Lingyu LiThe Cancer Center of the First Hospital of Jilin University, Changchun, Jilin 130021, People's Republic of China.
Xiao ChenThe Cancer Center of the First Hospital of Jilin University, Changchun, Jilin 130021, People's Republic of China.
Xiangliang LiuThe Cancer Center of the First Hospital of Jilin University, Changchun, Jilin 130021, People's Republic of China.
Yongfei ZhangThe Cancer Center of the First Hospital of Jilin University, Changchun, Jilin 130021, People's Republic of China.
Jiuwei CuiThe Cancer Center of the First Hospital of Jilin University, Changchun, Jilin 130021, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough MATERIALS AND

methodsUsing data from The Cancer Genome Atlas Program (TCGA) and Cancer Proteome Atlas, TMB and protein level of PD-L1 were explored in the patients with

resultsThis study analyzed somatic mutation data from 1287 patients from five cohorts (TCGA, Broad, The Tumour Sequencing Project, Memorial Sloan Kettering Cancer Center, Catalogue Of Somatic Mutations In Cancer database). The probability of

conclusionIn this study, we defined a subgroup of patients with

Indexed as

EGFR mutationepidermal growth factor receptorICIimmune checkpoint inhibitorLUADlung adenocarcinomaTMBtumor mutation burden

Identifiers

PMID32982525
PMCPMC7490071

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.