ArticleRisk management and healthcare policy2020
Depression and Perceived Stress, but Not Anxiety, are Associated with Elevated Inflammation in an Obese Adult Population.
Article in Risk management and healthcare policy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Effects of Sodium Benzoate, a D-Amino Acid Oxidase Inhibitor, on Perceived Stress and Cognitive Function Among Patients With Late-Life Depression: A Randomized, Double-Blind, Sertraline- and Placebo-Controlled Trial.The international journal of neuropsychopharmacology · 2022Trial
- Article
- Impact of Dysmenorrhea Severity on Mental Wellbeing and Quality of Life Among Saudi Women: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- Biological, environmental, and psychological stress and the human gut microbiome in healthy adults.Scientific reports · 2025Article
- Network study of the nutritional patterns, the metabolic and the psychological status among overweight-obese young adults.Frontiers in nutrition · 2025Article
- Work Addiction and Depression, Anxiety, and Stress: the Mediating Role of Food Addiction Among Lebanese Young Adult Workers.International journal of mental health and addiction · 2022Article
- Exaggerated amygdala response to threat and association with immune hyperactivity in depression.Brain, behavior, and immunity · 2022Article
- COVID-19-related stress in postpartum women from Argentina during the second wave in 2021: Identification of impairing and protective factors.Midwifery · 2022Article
- Elevated highly sensitive C-reactive protein in fibromyalgia associates with symptom severity.Rheumatology advances in practice · 2022Article
- Perceived Stress and Interest in Non-Invasive Aesthetic Procedures During the COVID-19 Pandemic.Clinical, cosmetic and investigational dermatology · 2022Article
- Childhood adversities and the comorbidity between mood and general medical disorders in adults: Results from the WHO World Mental Health Survey Portugal.Brain, behavior, & immunity - health · 2021Article
- The Mediating Role of Daily Affect Dynamics in Bidirectional and Longitudinal Associations Between Depressive Symptoms and Inflammation.Biopsychosocial science and medicineArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnxiety, depression and perceived stress are risk factors for adverse health problems. Inflammation participates in the development of chronic diseases such as psychiatric disorders. This study explored the relationships between inflammatory biomarkers and depression, anxiety and perceived stress in an obese adult population.
methodsThe relationships between psychological scores and inflammatory markers were analyzed.
resultsA higher BMI was not correlated with a higher anxiety score (P=0.152); however, BMI was positively associated with a higher depression score (P<0.001) and a higher perceived stress score (P<0.001). Multivariate linear regression analysis revealed that in participants with BMI≥30 and 25≤BMI<30, depression and perceived stress were significantly and independently associated with ICAM-1, E-selectin and CRP, but these associations were not observed in participants with BMI<25. The anxiety score was not associated with any inflammatory marker in any group of subjects, as determined by multivariate analysis.
conclusionDepression and perceived stress were strongly associated with increased serum levels of pro-inflammatory markers, including ICAM-1, E-selectin and CRP, among a general obese population from the United States. These results further suggest that depression and perceived stress might also be chronic systemic inflammatory diseases.
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