ArticleJournal of experimental pharmacology2020
Chemo Suppressive and Curative Potential of
Article in Journal of experimental pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- In silico and in vivo assessment of the immunostimulatory activity of palmitic acid derived from Vernonia amygdalina.Scientific reports · 2025Article
- Isolation and validation of antimalarial compounds from Phyllanthus emblica leaves for new antimalarial drug development.Scientific reports · 2025Article
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- Antimalarial and Immunomodulatory Activities ofScientifica · 2024Article
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- Quest for malaria management using natural remedies.Frontiers in pharmacology · 2024Review
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- Evaluation of the Anti-Malarial Activity of the Crude Root Extract and Solvent Fraction ofJournal of experimental pharmacology · 2023Article
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- Suppressive, Curative, and Prophylactic Effects ofBioMed research international · 2022Article
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- Studies on Activities and Chemical Characterization of Medicinal Plants in Search for New Antimalarials: A Ten Year Review on Ethnopharmacology.Frontiers in pharmacology · 2021Review
- Antiplasmodial Activity of the Crude Extract and Solvent Fractions of Stem Barks ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Antimalarial Activity ofJournal of experimental pharmacology · 2020Article
- Synergistic Interaction of Chloroquine withIranian journal of pharmaceutical research : IJPRArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe emergence of drug resistance together with the global burden of malaria triggers the necessity for the searching of new antimalarial agents. This study, therefore, was initiated to investigate the in vivo antimalarial activity of
methodsThe 4-day suppressive (crude extract and fractions) and the Rane's (n-butanol fraction) tests were used to evaluate the antimalarial activity of the plant. A cold maceration technique with 80% methanol was used for the crude extraction of the plant. The crude extract was then fractionated using solvents of different polarity (chloroform, n-butanol, and water).
resultsAll the test doses of the crude extract as well as the fractions reduced parasitemia and prolonged mean survival time significantly (
conclusionThe study has revealed that the plant has a promising antimalarial activity, the activity being more in the crude extract than the fractions. The highest antimalarial activity of the n-butanol fraction suggests that non-polar and medium polar principles could be responsible for the observed activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.