ReviewClinical interventions in aging2020
Preserving Mobility in Older Adults with Physical Frailty and Sarcopenia: Opportunities, Challenges, and Recommendations for Physical Activity Interventions.
Review in Clinical interventions in aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07205133 (Effectiveness of Whole Body Vibration Therapy and Usual Care Compared to Usual Care in Improving Muscle Mass, Strength and Function in Older Adults), which is not on this map. Cited by 136 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Whole Body Vibration Therapy and Usual Care Compared to Usual Care in Improving Muscle Mass, Strength and Function in Older Adults
Who cites it
136 citing papers in PubMed, 4 syntheses or guidelines pooled it, 226 citations in OpenAlex.
- Impact of Frailty in Patients With Continuous-Flow Left Ventricular Assist Device Therapy in End-Stage Heart Failure: A Systematic Review and Meta-Analysis.Artificial organs · 2025Pooled it
- Indoor mobility challenges among older adults: A systematic review of barriers and limitations.PloS one · 2025Pooled it
- Performance of digital technologies in assessing fall risks among older adults with cognitive impairment: a systematic review.GeroScience · 2024Pooled it
- Measures of perceived mobility ability in community-dwelling older adults: a systematic review of psychometric properties.Age and ageing · 2023Pooled it
- Frailty phenotype transitions and functional improvements during a supervised exercise trial in older people with HIV: results from the HEALTH Trial.Age and ageing · 2026Trial
- Effect of cerebellar vermis intermittent theta-burst stimulation on balance function in frail older adults: a randomized controlled trial.BMC geriatrics · 2026Trial
- The Effect of Digital Literacy Training on Physical Activity App Acceptance and Behavioral Intentions Among Older Women: An Experimental Study.International journal of environmental research and public health · 2026Trial
- Prediction and mediation analysis for treatment responses to combined cognitive and physical training for older adults.Scientific reports · 2024Trial
- Insulin Glargine is More Suitable Than Exenatide in Preventing Muscle Loss in Non-Obese Type 2 Diabetic Patients with NAFLD.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2023Trial
- Effectiveness of elastic band training and group-based dance on physical-functional performance in older women with sarcopenia: a pilot study.BMC public health · 2023Trial
- Trial
- The Added Value of Point-Light Display Observation in Total Knee Arthroplasty Rehabilitation Program: A Prospective Randomized Controlled Pilot Study.Medicina (Kaunas, Lithuania) · 2022Trial
- The sarcopenia and physical frailty in older people: multi-component treatment strategies (SPRINTT) project: description and feasibility of a nutrition intervention in community-dwelling older Europeans.European geriatric medicine · 2021Trial
- Moderate-to-Vigorous Physical Activity, Muscle Function, and Contemporary Sarcopenia Definitions in Older Adults With HIV.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- The association between the degree of frailty and the risk of hospital related adverse events in older acutely admitted patients.Age and ageing · 2026Observational
- Oral function and physical function converge: national evidence linking functional teeth, scaling care, and muscle strength.BMC geriatrics · 2026Article
- Unpacking the association of activities of daily living on self-care ability in China's rural empty-nest older adults: the chain mediation of social alienation and psychological resilience.BMC geriatrics · 2026Article
- Assessing frailty in aged zebrafish using a quick pseudo-frailty index.Biology open · 2026Article
- Associations of "weekend warrior" and other physical activity patterns with sarcopenia among older adults in China: a cross-sectional study.BMC public health · 2026Article
- Risk of Sarcopenia, Anxiety and Depression Among Healthcare Professionals in Disability Care Facilities.Journal of frailty, sarcopenia and falls · 2026Article
76 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 13 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most widely conserved hallmarks of aging is a decline in functional capabilities. Mobility loss is particularly burdensome due to its association with negative health outcomes, loss of independence and disability, and the heavy impact on quality of life. Recently, a new condition, physical frailty and sarcopenia, has been proposed to define a critical stage in the disabling cascade. Physical frailty and sarcopenia are characterized by weakness, slowness, and reduced muscle mass, yet with preserved ability to move independently. One of the strategies that have shown some benefits in combatting mobility loss and its consequences for older adults is physical activity. Here, we describe the opportunities and challenges for the development of physical activity interventions in people with physical frailty and sarcopenia. The aim of this article is to review age-related physio(patho)logical changes that impact mobility in old age and to provide recommendations and procedures in accordance with the available literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.