Evidence map›Paper›PMID 32982096›Full record

ArticleAnnals of neurosciences2020

Interleukin-17 and Interleukin-10 Association with Disease Progression in Schizophrenia.

Raghavi Chenniappan, Hanumanthappa Nandeesha, Shivanand Kattimani, Nandakumar Dalavaikodihalli Nanjaiah

Open access · diamondAbstract read
In one paragraph

Article in Annals of neurosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.6field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  6. Article
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  8. Article
  9. Microglia and Microbiome-Gut-Brain Axis.Advances in neurobiology · 2024
    Review
  10. Article
  11. Review
  12. Dysregulation of Synaptic Plasticity Markers in Schizophrenia.Indian journal of clinical biochemistry : IJCB · 2023
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Raghavi ChenniappanDepartment of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Hanumanthappa NandeeshaDepartment of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Shivanand KattimaniDepartment of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Nandakumar Dalavaikodihalli NanjaiahDepartment of Neurochemistry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Jawaharlal Institute of Post Graduate Medical Education and Research · INNational Institute of Mental Health and Neurosciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlteration in cytokine levels are known to be involved in the pathogenesis of schizophrenia.

objectivesTo estimate the serum levels of interleukin-17 (IL-17) and interleukin-10 (IL-10) and their association with disease progression in schizophrenia.

methodsA total of 67 schizophrenia cases were enrolled in the present study. IL-17 and IL-10 were estimated by enzyme-linked immunosorbent assay. Positive and Negative Syndrome Scale (PANSS) was used to evaluate disease severity.

resultsIL-17 was positively correlated with positive symptom score (

conclusionIL-17 and IL-10 are associated with disease severity in schizophrenia but are not good markers for predicting the disease progression.

Indexed as

cytokinesdisease progressinflammationinterleukinspsychopathologySchizophrenia

Identifiers

PMID32982096
PMCPMC7499827
OpenAlexW3082689602

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.