Evidence map›Paper›PMID 32982068›Full record

ArticlePteridines2020

Plasma soluble P-selectin correlates with triglycerides and nitrite in overweight/obese patients with schizophrenia.

Katelynn A Bourassa, Teodor T Postolache, Aline Dagdag, Dietmar Fuchs, Olaoluwa O Okusaga

Open access · goldAbstract read
In one paragraph

Article in Pteridines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Katelynn A BourassaMichael E. DeBakey VA Medical Center, Houston, TX, USA.
Teodor T PostolacheMood and Anxiety Program, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA, Veterans Health Administration, Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), Denver Veterans Affairs Medical Center (VAMC), Aurora, CO, USA, Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Aurora, CO, USA, VISN 5 Capitol Health Care Network Mental Illness Research Education and Clinical Center (MIRECC), Baltimore, MD, USA.
Aline DagdagMood and Anxiety Program, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Dietmar FuchsDivision of Biological Chemistry, Biocenter Innsbruck Medical University, Innsbruck, Austria.
Olaoluwa O OkusagaMichael E. DeBakey VA Medical Center, Houston, TX, USA, Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Michael E. DeBakey VA Medical Center · USInnsbruck Medical University · ATUniversity of Maryland, Baltimore · USVeterans Health Administration · US

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
NIDDK NIH HHS P30 DK072488
6 · The paper itself

Abstract

backgroundSoluble P-selectin (sP-selectin) is associated with risk factors for cardiovascular disease (CVD) but this association has not been evaluated in patients with schizophrenia. This study primarily evaluated the association of sP-selectin with plasma lipids and nitrite (NO

methodsOne-hundred and six patients with schizophrenia (mean age 32.9 years; 71.60% male) were recruited from a psychiatric hospital. Participants completed a structured interview and provided a fasting blood sample. Body mass index (BMI) was used to divide the sample into normal weight and overweight/obese groups. Pearson's and partial correlation coefficients (controlling for age, sex, race, education, and inflammation) were calculated to examine the association of sP-selectin with plasma lipids, and NO

resultsAfter controlling for potential confounders, sP-selectin positively correlated with triglycerides (

conclusionsFuture longitudinal studies should evaluate the utility of sP-selectin as a biomarker of CVD in overweight/obese adults with schizophrenia (for example, by relating sP-selectin to incidence of cardiovascular events).

Indexed as

atherosclerosisnitriteoverweight/obesityP-selectinschizophrenia

Identifiers

PMID32982068
PMCPMC7518413
OpenAlexW3032934507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.