Evidence map›Paper›PMID 32982062›Full record

ReviewTrends in food science & technology2020

anti-HCoV: A web resource to collect natural compounds against human coronaviruses.

Francesco Monticolo, Emanuela Palomba, Rosa De Santis, Lorenzo Assentato, Viviana Triscino, Maria Chiara Langella, Virginia Lanzotti, Maria Luisa Chiusano

Abstract readReview
In one paragraph

Review in Trends in food science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco MonticoloDepartment of Agricultural Sciences, Università degli studi di Napoli Federico II, Reggia di Portici - Via Università, 100 - 80055, Portici (NA), Italy.
Emanuela PalombaDepartment of Research Infrastructures for marine biological resources (RIMAR), Stazione Zoologica "Anton Dohrn", Villa Comunale 80121 - Napoli, Italy.
Rosa De SantisDepartment of Agricultural Sciences, Università degli studi di Napoli Federico II, Reggia di Portici - Via Università, 100 - 80055, Portici (NA), Italy.
Lorenzo AssentatoDepartment of Agricultural Sciences, Università degli studi di Napoli Federico II, Reggia di Portici - Via Università, 100 - 80055, Portici (NA), Italy.
Viviana TriscinoDepartment of Agricultural Sciences, Università degli studi di Napoli Federico II, Reggia di Portici - Via Università, 100 - 80055, Portici (NA), Italy.
Maria Chiara LangellaDepartment of Agricultural Sciences, Università degli studi di Napoli Federico II, Reggia di Portici - Via Università, 100 - 80055, Portici (NA), Italy.
Virginia LanzottiDepartment of Agricultural Sciences, Università degli studi di Napoli Federico II, Reggia di Portici - Via Università, 100 - 80055, Portici (NA), Italy.
Maria Luisa ChiusanoDepartment of Agricultural Sciences, Università degli studi di Napoli Federico II, Reggia di Portici - Via Università, 100 - 80055, Portici (NA), Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA novel coronavirus, the SARS-CoV2, was revealed to be the cause of COVID19, the pandemic disease that already provoked more than 555.324 deaths in the world (July 10, 2020). No vaccine treatment has been defined against SARS-CoV2 or other human coronaviruses (HCoVs), including those causing epidemic infections, neither appropriate strategies for prevention and care are yet officially suggested. SCOPE AND APPROACH: We reviewed scientific literature on natural compounds that were defined as potentially effective against human coronaviruses. Our desk research identified non-chemically modified natural compounds that were shown (in vitro) and/or predicted (in silico) to act against one or more phases of human coronaviruses cell cycle.We selected all available information, merged and annotated the data to define a comprehensive list of natural compounds, describing their chemical classification, the source, the action, the specific target in the viral infection. Our aim was to collect possible compounds for prevention and care against human coronaviruses. KEY FINDINGS AND

conclusionsThe definition of appropriate interventions against viral diseases need a comprehensive view on the infection dynamics and on necessary treatments. Viral targeting compounds to be exploited in food sciences could be of relevant interest to this aim.We collected 174 natural compounds showing effects against human infecting coronaviruses, providing a curated annotation on actions and targets.The data are available in

Indexed as

Antiviral compounds-natural productsMERSSARSViral fightWeb based resource

Identifiers

PMID32982062
PMCPMC7505852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.