Evidence map›Paper›PMID 32981954›Full record

ArticleThe journal of extra-corporeal technology2020

Evaluating Changes in del Nido Cardioplegia Practices in Adult Cardiac Surgery.

Donald S Likosky, Xiaoting Wu, David C Fitzgerald, Jonathan W Haft, Gaetano Paone, Matthew A Romano, Joshua B Goldberg, Alphonse DeLucia, David L Sturmer, David M Grix and 4 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The journal of extra-corporeal technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. 2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Donald S LikoskyDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Xiaoting WuDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
David C FitzgeraldDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Jonathan W HaftDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Gaetano PaoneDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Matthew A RomanoDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Joshua B GoldbergDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Alphonse DeLuciaDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
David L SturmerDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
David M GrixDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Donald H NieterDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Brittney N GraebnerDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
Timothy A DickinsonDepartment of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor, Michigan; Medical University of South Carolina, Charleston, South Carolina; Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; New York Medical College, Westchester Medical Center, Valhalla, New York; Department of Cardiac Surgery, Bronson Methodist Hospital, Kalamazoo, Michigan; Perfusion Associates of Michigan, Saginaw, Michigan; and Mayo Clinic, Rochester, Minnesota.
PERForm Registry and the Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative
Michigan Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been a rapid adoption of the use of del Nido cardioplegia (DC) among adults undergoing cardiac surgery. We leveraged a multicenter database to evaluate differences over time in the choice and impact of cardioplegia type (DC vs. blood) among patients undergoing cardiac surgery. We evaluated 26,373 patients undergoing non-emergent coronary artery bypass and/or valve surgery between 2014-2015 (early period) and 2017-2018 (late period) at 31 centers. DC was compared with blood-based cardioplegia (BC: 1:1, 2:1, 4:1, 8:1, and variable ratio). We evaluated whether treatment choice differed across prespecified patient characteristics, procedure type, and perfusion practices by time period. We evaluated increased DC use with clinical outcomes (major morbidity and mortality, prolonged intubation, and renal failure), after adjusting for baseline characteristics, procedure type, center, and year. DC use increased from 19.6% in 2014-2015 to 41.5% in 2017-2018,

Indexed as

Cardioplegic SolutionsHeart Arrest, InducedAdultCoronary Artery BypassHumansCardioplegic SolutionsCABGcoronary artery bypass graftsdel Nido cardioplegia

Identifiers

PMID32981954
PMCPMC7499224
OpenAlexW3088294066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.