Evidence map›Paper›PMID 32981568›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2020

Effects of the lockdown on the mental health of the general population during the COVID-19 pandemic in Italy: Results from the COMET collaborative network.

Andrea Fiorillo, Gaia Sampogna, Vincenzo Giallonardo, Valeria Del Vecchio, Mario Luciano, Umberto Albert, Claudia Carmassi, Giuseppe Carrà, Francesca Cirulli, Bernardo Dell'Osso and 5 more

Abstract read
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 204 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
204citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

204 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  9. Anxiety Linked to COVID-19: A Systematic Review Comparing Anxiety Rates in Different Populations.International journal of environmental research and public health · 2022
    Pooled it
  10. Prevalence of Anxiety in University Students during the COVID-19 Pandemic: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
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  14. Indirect, machine learning-based suicide risk screening: Evidence from cross-National Validation.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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144 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Andrea FiorilloDepartment of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.
Gaia SampognaDepartment of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.
Vincenzo GiallonardoDepartment of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.ORCID 0000-0003-3294-1748
Valeria Del VecchioDepartment of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.
Mario LucianoDepartment of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.
Umberto AlbertDepartment of Medicine, Surgery and Health Sciences, University of Trieste and Department of Mental Health, Azienda Sanitaria Universitaria Giuliano Isontina - ASUGI, Trieste, Italy.
Claudia CarmassiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Giuseppe CarràDepartment of Medicine and Surgery, University of Milan Bicocca, Milan, Italy.ORCID 0000-0002-6877-6169
Francesca CirulliCenter for Behavioral Sciences and Mental Health, National Institute of Health, Rome, Italy.ORCID 0000-0001-9440-1873
Bernardo Dell'OssoDepartment of Biomedical and Clinical Sciences Luigi Sacco and Aldo Ravelli Center for Neurotechnology and Brain Therapeutic, University of Milan, Milano, Italy.
Maria Giulia NanniInstitute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.
Maurizio PompiliDepartment of Neurosciences, Mental Health and Sensory Organs, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.ORCID 0000-0003-1886-4977
Gabriele SaniDepartment of Neuroscience, Section of Psychiatry, University Cattolica del Sacro Cuore, Rome, Italy.
Alfonso TortorellaDepartment of Psychiatry, University of Perugia, Perugia, Italy.
Umberto VolpeClinical Psychiatry Unit, Department of Clinical Neurosciences, Università Politecnica delle Marche, Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Coronavirus disease 2019 (COVID-19) pandemic is an unprecedented traumatic event influencing the healthcare, economic, and social welfare systems worldwide. In order to slow the infection rates, lockdown has been implemented almost everywhere. Italy, one of the countries most severely affected, entered the "lockdown" on March 8, 2020.

methodsThe COvid Mental hEalth Trial (COMET) network includes 10 Italian university sites and the National Institute of Health. The whole study has three different phases. The first phase includes an online survey conducted between March and May 2020 in the Italian population. Recruitment took place through email invitation letters, social media, mailing lists of universities, national medical associations, and associations of stakeholders (e.g., associations of users/carers). In order to evaluate the impact of lockdown on depressive, anxiety and stress symptoms, multivariate linear regression models were performed, weighted for the propensity score.

resultsThe final sample consisted of 20,720 participants. Among them, 12.4% of respondents (N = 2,555) reported severe or extremely severe levels of depressive symptoms, 17.6% (N = 3,627) of anxiety symptoms and 41.6% (N = 8,619) reported to feel at least moderately stressed by the situation at the DASS-21.According to the multivariate regression models, the depressive, anxiety and stress symptoms significantly worsened from the week April 9-15 to the week April 30 to May 4 (p < 0.0001). Moreover, female respondents and people with pre-existing mental health problems were at higher risk of developing severe depression and anxiety symptoms (p < 0.0001).

conclusionsAlthough physical isolation and lockdown represent essential public health measures for containing the spread of the COVID-19 pandemic, they are a serious threat for mental health and well-being of the general population. As an integral part of COVID-19 response, mental health needs should be addressed.

Indexed as

Health SurveysAdolescentAdultAgedAnxietyBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansItalyMaleMental HealthMiddle AgedPandemicsPneumonia, ViralAnxietyCOVID-19depressionlockdownpandemicstress

Identifiers

PMID32981568
PMCPMC7556907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.