Evidence map›Paper›PMID 32981541›Full record

ArticleParasitology2021

Alternative pathways in

David Modrý, Barbora Fecková, Barbora Putnová, Sheina Macy Manalo, Domenico Otranto

Open access · greenAbstract read
In one paragraph

Article in Parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. PatentFrontiers in veterinary science · 2025
    Article
  8. Passage ofParasitology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Prevalence ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  13. Article
  14. Rat lungworm (Parasitology · 2023
    Article
  15. An Overview ofPathogens (Basel, Switzerland) · 2023
    Review
  16. Pathogens (Basel, Switzerland) · 2022
    Review
  17. Pathogens (Basel, Switzerland) · 2022
    Article
  18. Endemic lizardParasitology · 2022
    Article
  19. Review
  20. Angiostrongylosis in Animals and Humans in Europe.Pathogens (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 4 countries.

David ModrýUniversity of Veterinary and Pharmaceutical Sciences, Palackého tř. 1946/1, Brno, Czech Republic.ORCID 0000-0001-9649-6255
Barbora FeckováUniversity of Veterinary and Pharmaceutical Sciences, Palackého tř. 1946/1, Brno, Czech Republic.ORCID 0000-0001-9091-9894
Barbora PutnováUniversity of Veterinary and Pharmaceutical Sciences, Palackého tř. 1946/1, Brno, Czech Republic.
Sheina Macy ManaloUniversity of Veterinary and Pharmaceutical Sciences, Palackého tř. 1946/1, Brno, Czech Republic.
Domenico OtrantoDipartimento di Medicina Veterinaria, Università degli Studi di Bari, Bari, Italy.ORCID 0000-0002-7518-476X
University of Veterinary Sciences Brno · CZBu-Ali Sina University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to elucidate the infection pathways of third stage larvae (L3) of Angiostrongylus cantonensis, we performed experiments to assess: (i) the shedding of L3 from two species of experimental veronicellid slugs drowned in water and the ratio of emerged larvae, (ii) the transmission of viable L3 from drowned terrestrial gastropods to aquatic snails, and (iii) the transmission of viable L3 between terrestrial snails. Molluscs were experimentally infected by first stage larvae (L1) of A. cantonensis. Significantly more L3 larvae were released from Veronicella cubensis than from Veronicella sloanei. Numerous L3 were observed in the muscular foot, and also in the connective tissue between internal organs. Experimental exposure of P. maculata to L3 of A. cantonensis liberated from other gastropod species led to their infection and the infectivity of larvae after intermediesis was demonstrated by infection of laboratory rats (Rattus norvegicus). The transmission of L3 was observed in three out of four experiment replications and L3 were retrieved from 6 out of 24 Subulina octona snails. The infected synanthropic molluscs represent a key component in the epidemiology of human infections by A. cantonensis. Escape of L3 larvae from bodies of dead snails or slugs and their ability to infect further gastropod hosts (intermediesis) represents a public health risk. Thus, control of molluscs living in peri-domestic environment is an essential part of prevention of human infections.

Indexed as

Angiostrongylus cantonensisAnimalsFemaleGastropodaLarvaRatsRats, WistarSpecies SpecificityStrongylida InfectionsAngiostrongylus cantonensisdiseaseemergingexperimental infectionintermediesiszoonosis

Identifiers

PMID32981541
PMCPMC11010052
OpenAlexW3087846588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.