ArticleJournal of the American Heart Association2020
Sex Differences in Modifiable Risk Factors and Severity of Coronary Artery Disease.
Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01218776 (International Survey of Acute Coronary Syndromes), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
International Survey of Acute Coronary Syndromes
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Exploring associations between estrogen and gene candidates identified by coronary artery disease genome-wide association studies.Frontiers in cardiovascular medicine · 2025Pooled it
- Add-Ons of Heart Disease from the Cardiosurgical Perspective: Gender, Blood Groups and Renal Function.Medical sciences (Basel, Switzerland) · 2026Article
- Microvascular Dysfunction in MINOCA: Still a Moving Target.Journal of the American Heart Association · 2026Article
- Sex Disparities in Ischemic Heart Disease Death Across the United States: The Southern Burden of Excess Body Weight and Diet.Journal of the American Heart Association · 2026Article
- Prognostic Impact of Infarct Size and Coronary Microvascular Function Via Cardiovascular Magnetic Resonance and Coronary Angiography-Derived Index of Microcirculatory Resistance in Myocardial Infarction With Nonobstructive Coronary Arteries.Journal of the American Heart Association · 2026Observational
- A comprehensive review of ischemic heart disease: pathophysiology, current treatments, natural products-based therapies, and nanotherapeutics.Frontiers in pharmacology · 2026Review
- Temporal trends in acute coronary syndrome among women and association with socioeconomic factors-evidence from a middle-income country.Frontiers in global women's health · 2026Article
- Factors associated with all-cause mortality in endovascularly treated patients with chronic limb-threatening ischemia.Frontiers in epidemiology · 2026Article
- Gender Differences in Major Risk Factors for Cardiovascular Disease in Mexican Adults.Global heart · 2026Article
- Coronary revascularization and sex differences in cardiovascular mortality after myocardial infarction in 12 high and middle-income European countries.European heart journal. Quality of care & clinical outcomes · 2025Article
- Changing clinical perspectives on sex and healthcare disparities in ischaemic heart disease.The Lancet regional health. Europe · 2025Review
- Age and sex differences in the efficacy of early invasive strategy for non-ST-elevation acute coronary syndrome: A comparative analysis in stable patients.American journal of preventive cardiology · 2025Article
- Anticancer-Drug-Related Cardiotoxicity from Adjuvant Goserelin and Tamoxifen Therapy.Journal of clinical medicine · 2025Article
- Epidemiology of Rounding Error.Medicina (Kaunas, Lithuania) · 2024Article
- Sex Disparities in Ischemic Heart Disease Mortality in Europe.JACC. Advances · 2024Article
- Sex disparities in mortality and cardiovascular outcomes in chronic kidney disease.Clinical kidney journal · 2024Review
- Comprehensive evaluation of smoking exposures and their interactions on DNA methylation.EBioMedicine · 2024Article
- Clinical predictive factors of coronary stenosis in patients with high‑risk valvular heart disease who received diagnostic coronary angiography prior to cardiac valve surgery.Biomedical reports · 2024Article
- Clinical determinants of ischemic heart disease in Eastern Europe.The Lancet regional health. Europe · 2023Review
- Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction-A Systematic Review.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 7 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background It is still unknown whether traditional risk factors may have a sex-specific impact on coronary artery disease (CAD) burden. Methods and Results We identified 14 793 patients who underwent coronary angiography for acute coronary syndromes in the ISACS-TC (International Survey of Acute Coronary Syndromes in Transitional Countries; ClinicalTrials.gov, NCT01218776) registry from 2010 to 2019. The main outcome measure was the association between traditional risk factors and severity of CAD and its relationship with 30-day mortality. Relative risk (RR) ratios and 95% CIs were calculated from the ratio of the absolute risks of women versus men using inverse probability of weighting. Estimates were compared by test of interaction on the log scale. Severity of CAD was categorized as obstructive (≥50% stenosis) versus nonobstructive CAD. The RR ratio for obstructive CAD in women versus men among people without diabetes mellitus was 0.49 (95% CI, 0.41-0.60) and among those with diabetes mellitus was 0.89 (95% CI, 0.62-1.29), with an interaction by diabetes mellitus status of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.