Evidence map›Paper›PMID 32981382›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Design, synthesis, and evaluation of novel

Le Cong Huan, Duong Tien Anh, Pham-The Hai, Lai Duc Anh, Eun Jae Park, A Young Ji, Jong Soon Kang, Do Thi Mai Dung, Dao Thi Kim Oanh, Truong Thanh Tung and 3 more

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Le Cong HuanHanoi University of Pharmacy, Hanoi, Vietnam.
Duong Tien AnhHanoi University of Pharmacy, Hanoi, Vietnam.
Pham-The HaiHanoi University of Pharmacy, Hanoi, Vietnam.ORCID https://orcid.org/0000-0003-4531-7223
Lai Duc AnhHanoi University of Pharmacy, Hanoi, Vietnam.
Eun Jae ParkCollege of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea.
A Young JiCollege of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea.
Jong Soon KangBio-Evaluation Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Republic of Korea.
Do Thi Mai DungHanoi University of Pharmacy, Hanoi, Vietnam.
Dao Thi Kim OanhHanoi University of Pharmacy, Hanoi, Vietnam.
Truong Thanh TungFaculty of Pharmacy, PHENIKAA University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0002-5263-203X
Dinh Thi Thanh HaiHanoi University of Pharmacy, Hanoi, Vietnam.
Sang-Bae HanCollege of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea.
Nguyen-Hai NamHanoi University of Pharmacy, Hanoi, Vietnam.ORCID https://orcid.org/0000-0001-8475-2530

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In continuity of our search for novel anticancer agents acting as procaspase activators, we have designed and synthesised two series of (

Indexed as

Antineoplastic AgentsApoptosisCaspase InhibitorsCaspases, InitiatorCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansHydrazinesIsatinMolecular Docking SimulationStructure-Activity RelationshipAntineoplastic AgentscarbohydrazideCaspase InhibitorsCaspases, InitiatorHydrazinesIsatinAcetohydrazidescaspase activationcytotoxicityisatin

Identifiers

PMID32981382
PMCPMC7534272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.