Evidence map›Paper›PMID 32981004›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2021

Statistical control of processes applied to geometric uncertainties for CTV expansion margins determination in prostate cancer patients treated with VMAT: a prospective study in 57 patients.

J Pardo, J González, N Aymar, I Ortiz, B Rodriguez, D Morera, A Guerrero, A M Mena, J Font

Abstract read
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In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Statistical process control to monitor use of a web-based autoplanning tool.Journal of applied clinical medical physics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

J PardoRadiation Oncology Department, Hospital Universitari Son Espases, Carretera de Valldemossa 79, 07020, Palma de Mallorca, Spain. jose.pardo@ssib.es.ORCID http://orcid.org/0000-0003-0921-0066
J GonzálezHospital Universitari General de Catalunya, Sant Cugat del Vallès, Spain.
N AymarRadiation Oncology Department, Hospital Universitari Son Espases, Carretera de Valldemossa 79, 07020, Palma de Mallorca, Spain.
I OrtizRadiation Oncology Department, Hospital Universitari Son Espases, Carretera de Valldemossa 79, 07020, Palma de Mallorca, Spain.
B RodriguezIMQ Zorrotzaurre, Bilbao, Spain.
D MoreraRadiation Oncology Department, Hospital Miramar-Juaneda, Palma de Mallorca, Spain.
A GuerreroRadiation Oncology Department, Hospital Universitari Son Espases, Carretera de Valldemossa 79, 07020, Palma de Mallorca, Spain.
A M MenaRadiation Oncology Department, Hospital Universitari Son Espases, Carretera de Valldemossa 79, 07020, Palma de Mallorca, Spain.
J FontMedical Physics Department, Hospital Universitari Son Espases, Palma de Mallorca, Spain.
Health Research Institute of the Balearic Islands · ESHospital General de Catalunya · ESClinic IMQ Zorrotzaurre · ESHospital Universitario Son Espases · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the control graphs applicability for the geometric uncertainties of VMAT treatments in prostate cancer patients, and their use to verify the hypothesis of the data obtained randomness, to apply the margins of Van Herk expression. MATERIAL AND

methodsDuring the first 5 days of treatment, and then once a week, a Kv CBCT was performed, compared with the simulation CT and adjusted the displacements, to determine the inter-fraction errors. Immediately after radiation therapy, another CBCT was performed (for intra-fraction errors). With these data, the X, R position control charts have been made. The patients, not maintained the deviations within the charts control limits, were called "anomalies". Then, we compared the deviations and margins calculated with the van Herk expression for all patients and for those without anomalies.

resultsThe margins determined show appreciable differences if there were calculated for the total set of patients or for the set of them without anomalies in the control charts. For the overall set of patients, the lateral, longitudinal, and vertical margins were 0.45 cm, 0.52 cm, 0.56 cm, while for the set of patients without anomalies were 0.29 cm, 0.35 cm, and 0.38 cm.

conclusionsThe use of control charts allows tracking geometric deviations both inter and intra-fraction, variability real-time control and to detect situations in which it can change for non-random reasons, and require immediate investigation. Maintaining geometric deviations in the control state decreases the margins needed to administer a high dose to CTV in a high percentage of cancer prostate patients.

Indexed as

Radiotherapy DosageUncertaintyHumansMaleProspective StudiesProstatic NeoplasmsRadiotherapy, Intensity-ModulatedControl chartsControl state of geometric deviationsProstate cancer patientsVMAT treatments uncertainties

Identifiers

PMID32981004
OpenAlexW3088842346

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.