Evidence map›Paper›PMID 32980852›Full record

ArticleThe American journal of case reports2020

Delayed Diagnosis and Treatment of a Critically Ill Patient with Infective Endocarditis Due to a False-Positive Molecular Diagnostic Test for SARS-CoV-2.

Nikolaos Schizas, Theodoros Michailidis, Ilias Samiotis, Vasilios Patris, Konstantinos Papakonstantinou, Michail Argiriou, Panagiotis Dedeilias

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  6. Deciphering a Case of SARS-CoV-2Annals of laboratory medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nikolaos SchizasDepartment of Cardiovascular and Thoracic Surgery, Evangelismos General Hospital, Athens, Greece.
Theodoros MichailidisSecond Department of Internal Medicine, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece.
Ilias SamiotisDepartment of Cardiovascular and Thoracic Surgery, Evangelismos General Hospital, Athens, Greece.
Vasilios PatrisDepartment of Cardiovascular and Thoracic Surgery, Evangelismos General Hospital, Athens, Greece.
Konstantinos PapakonstantinouDepartment of General Surgery, Thoracic Diseases General Hospital Sotiria of Athens, Athens, Greece.
Michail ArgiriouDepartment of Cardiovascular and Thoracic Surgery, Evangelismos General Hospital, Athens, Greece.
Panagiotis DedeiliasDepartment of Cardiovascular and Thoracic Surgery, Evangelismos General Hospital, Athens, Greece.
Evangelismos Hospital · GRIppokrateio General Hospital of Thessaloniki · GRSotiria General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND The worldwide spread of the severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) has created unprecedented situations for healthcare professionals and healthcare systems. Although infection with this virus is considered the main health problem currently, other diseases are still prevalent. CASE REPORT This report describes a 59-year-old man who presented with symptoms of dyspnea and fever that were attributed to Covid-19 infection. His clinical condition deteriorated and further examinations revealed a subjacent severe aortic regurgitation due to acute infective endocarditis. Surgical treatment was successful. CONCLUSIONS The results of diagnostic tests for Covid-19 should be re-evaluated whenever there are clinical mismatches or doubts, as false-positive Covid-19 test results can occur. Clinical interpretation should not be determined exclusively by the Covid-19 pandemic. This case report highlights the importance of using validated and approved serological and molecular testing to detect infection with SARS-CoV-2, and to repeat tests when there is doubt about presenting symptoms.

Indexed as

Delayed DiagnosisAntibodies, ViralAortic Valve InsufficiencyCardiac Surgical ProceduresClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingCritical IllnessDisease ProgressionDyspneaEndocarditisFalse Positive ReactionsFeverHumansMaleAntibodies, Viral

Identifiers

PMID32980852
PMCPMC7526942
OpenAlexW3088914599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.