Evidence map›Paper›PMID 32979898›Full record

ArticleTurkish journal of medical sciences2021

The effect of Ankaferd blood stopper on liver damage in experimental obstructive jaundice

Koray Koşmaz, Abdullah Durhan, Marlen Süleyman, Yılmaz Ünal, Mustafa Taner Bostancı, Tuğba Yiğit Haskaraca, Can Ersak, Mehmet Şener, İlknur Alkan Kuşabbi, Eylem Pınar Eser and 1 more

Open access · greenAbstract read
In one paragraph

Article in Turkish journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. The effects of rose oil on liver damage in an experimental model of obstructive jaundice.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025
    Article
  3. Article
  4. Antineoplastic Effects of Ankaferd Hemostat.BioMed research international · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Koray KoşmazDepartment of General Surgery, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0003-2111-3162
Abdullah DurhanDepartment of General Surgery, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0002-5622-9678
Marlen SüleymanDepartment of General Surgery, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0001-6979-4150
Yılmaz ÜnalDepartment of General Surgery, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0001-9712-5827
Mustafa Taner BostancıDepartment of General Surgery, Dışkapı Education and Research Hospital, Ankara, TurkeyORCID 0000-0003-2876-2683
Tuğba Yiğit HaskaracaDepartment of General Surgery, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0003-2740-0269
Can ErsakDepartment of General Surgery, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0002-9658-6063
Mehmet ŞenerDepartment of Biochemistry, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0002-7924-5478
İlknur Alkan KuşabbiDepartment of Biochemistry, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0002-4932-1361
Eylem Pınar EserDepartment of Pathology, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0001-5459-4017
Sema HücümenoğluDepartment of Pathology, Ankara Education and Research Hospital, Ankara, TurkeyORCID 0000-0002-6898-4101
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aims: To evaluate the potential protective effects of Ankaferd blood stopper (ABS) in an experimental obstructive jaundice (OJ) model. Materials and methods: The study included 26 female rats, which were divided into 3 groups. The sham group, consisting of 10 rats, (group 1) only received solely laparotomy. In the control group, consisting of 8 rats, (group 2), ligation was applied to the biliary tract and no treatment was implemented. In the treatment group, consisting of 8 rats, (group 3), following ligation of biliary tract, 0.5 mL/day ABS was given for 10 days. Liver tissue and blood samples were taken for histopathological and biochemical examination. Results: Compared to group 2, group 3 had higher aspartate aminotransferase (AST), total oxidant status (TOS) malondialdehyde (MDA), fluorescent oxidant products (FOP), and lower expression of albumin and total antioxidant status (TAS) (P < 0.05). In histopathological analysis, the mean scores of all histopathological parameters (fibrosis, portal inflammation, confluent necrosis, interphase activity, bile duct proliferation) have statistical significance between group 2 and group 3 (P < 005). Conclusions: ABS has promising results in the treatment of experimental OJ because of its antioxidant and antiinflammatory properties. It may be used in clinical practice after more extensive studies about the effects of ABS on OJ.

Indexed as

Chemical and Drug Induced Liver InjuryJaundice, ObstructiveAnimalsAntioxidantsFemaleLiverOxidantsPlant ExtractsRatsRats, Wistarankaferd blood stopperAntioxidantsOxidantsPlant ExtractsAnkaferd blood stopperantioxidantObstructive jaundice

Identifiers

PMID32979898
PMCPMC8283441
OpenAlexW3089116109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.