Evidence map›Paper›PMID 32979856›Full record

ArticleMolecular microbiology2021

Deciphering the Che2 chemosensory pathway and the roles of individual Che2 proteins from Pseudomonas aeruginosa.

Emilie Orillard, Kylie J Watts

Open access · greenAbstract read
In one paragraph

Article in Molecular microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Microorganisms · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Diversity of bacterial chemosensory systems.Current opinion in microbiology · 2021
    Review
  12. Evidence for Pentapeptide-Dependent and Independent CheB Methylesterases.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Emilie OrillardDivision of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, CA, USA.ORCID 0000-0002-3872-0236
Kylie J WattsDivision of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, CA, USA.ORCID 0000-0002-8072-2745
Loma Linda University · US

Funding

Sensing, Signaling and the Role of Aer-2-Regulated Chemosensory SystemsR01GM108655 · NIGMS · LOMA LINDA UNIVERSITY · PI WATTS, KYLIE JANE · 2016 to 2020
$1.5M
NIGMS NIH HHS R01 GM108655
6 · The paper itself

Abstract

Pseudomonas aeruginosa is an opportunistic pathogen that senses and responds to its environment via four chemosensory systems. Oxygen activates the Che2 chemosensory system by binding to the PAS-heme domain of the Aer2 receptor. Ostensibly, the output of Che2 occurs via its response regulator CheY2, but controversy persists over CheY2's exact role. In this study, we show that CheY2 does not interact with the flagellar motor and that the Che2 system does not transfer phosphoryl groups to the chemotaxis (Che) system. We show that CheY2 instead provides feedback control of Aer2 adaptation. In the presence of O

Indexed as

Bacterial ProteinsCarrier ProteinsChemotaxisHistidine KinaseMembrane ProteinsMethyl-Accepting Chemotaxis ProteinsPhosphorylationPseudomonas aeruginosaSignal TransductionBacterial ProteinsCarrier ProteinsHistidine KinaseMembrane ProteinsMethyl-Accepting Chemotaxis Proteinsadaptationbacterial motilitychemosensingPseudomonas aeruginosaresponse regulatorsignal transduction

Identifiers

PMID32979856
PMCPMC7897226
OpenAlexW3088469780

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.