Evidence map›Paper›PMID 32979846›Full record

ReviewCurrent opinion in neurobiology2020

Cortico-cerebellar interactions during goal-directed behavior.

Nuo Li, Thomas D Mrsic-Flogel

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. The Hippocampus Preorders Movements for Skilled Action Sequences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. What networks in the brain system sustain imagination?Frontiers in network physiology · 2023
    Article
  15. How far neuroscience is from understanding brains.Frontiers in systems neuroscience · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nuo LiDepartment of Neuroscience, Baylor College of Medicine, United States. Electronic address: nuol@bcm.edu.
Thomas D Mrsic-FlogelSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, United Kingdom. Electronic address: t.mrsic-flogel@ucl.ac.uk.

Funding

Multi-regional neural circuit dynamics underlying short-term memoryR01NS113110 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI DRUCKMANN, SHAUL, LI, NUO · 2019 to 2023
$3.2M
Cortico-cerebellar interactions underlying motor planning and movementR01NS112312 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI LI, NUO · 2019 to 2023
$1.8M
NINDS NIH HHS R01 NS112312NINDS NIH HHS R01 NS113110Wellcome Trust
6 · The paper itself

Abstract

Preparatory activity is observed across multiple interconnected brain regions before goal-directed movement. Preparatory activity reflects discrete activity states representing specific future actions. It is unclear how this activity is mediated by multi-regional interactions. Recent evidence suggests that the cerebellum, classically associated with fine motor control, contributes to preparatory activity in the neocortex. We review recent advances and offer perspective on the function of cortico-cerebellar interactions during goal-directed behavior. We propose that the cerebellum learns to facilitate transitions between neocortical activity states. Transitions between activity states enable flexible and appropriately timed behavioral responses.

Indexed as

CerebellumGoalsLearningMovementNeural Pathways

Identifiers

PMID32979846
PMCPMC7770085

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.