Evidence map›Paper›PMID 32979763›Full record

ArticleCellular immunology2020

TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNα production.

Michelle L Ratliff, Malini Shankar, Joel M Guthridge, Judith A James, Carol F Webb

Open access · hybridAbstract read
In one paragraph

Article in Cellular immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michelle L RatliffDepartment of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Malini ShankarDepartment of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Joel M GuthridgeArthritis and Clinical Immunology Program, Oklahoma Medical Resource Foundation, Oklahoma City, OK 73104, USA; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Judith A JamesDepartment of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Arthritis and Clinical Immunology Program, Oklahoma Medical Resource Foundation, Oklahoma City, OK 73104, USA; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Carol F WebbDepartment of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA. Electronic address: carol-webb@ouhsc.edu.
University of Oklahoma Health Sciences Center · USOklahoma Medical Research Foundation · US

Funding

Tracking and Evaluation CoreU54GM104938 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI TIMOTHY M VANWAGONER · 2013 to 2026
$68.2M
Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Wade Williams · 2018 to 2026
$27.1M
Oklahoma Rheumatic Disease Research Cores Center (Overall Application)P30AR073750 · NIAMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI JUDITH A JAMES · 2018 to 2026
$8.5M
SNP Confirmation and High Throughput Genotyping CoreP30AR053483 · NIAMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI CHAKRAVARTY, ELIZA F · 2007 to 2017
$6.7M
Role of the transcription factor ARID3a in innate immune responsesR01AI118836 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI WEBB, CAROL F · 2017 to 2020
$1.5M
Role of ARID3a in aging human hematopoietic progenitor cellsR00AG055717 · NIA · EAST CAROLINA UNIVERSITY · PI RATLIFF, MICHELLE LEIGH · 2020 to 2022
$734k
Role of the Transcription Factor ARID3a in Innate Immune ResponsesR56AI118836 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI WEBB, CAROL F · 2015 to 2015
$370k
Role of ARID3a in aging human hematopoietic progenitor cellsK99AG055717 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI RATLIFF, MICHELLE LEIGH · 2017 to 2018
$189k
Identification of Proteins Interacting with ARID3aR03AI123951 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI WEBB, CAROL F · 2016 to 2017
$148k
NCI NIH HHS P30 CA225520NIAID NIH HHS R01 AI118836NIAID NIH HHS R03 AI123951NIAID NIH HHS R56 AI118836NIAMS NIH HHS P30 AR053483NIAMS NIH HHS P30 AR073750NIA NIH HHS K99 AG055717NIA NIH HHS R00 AG055717NIGMS NIH HHS U54 GM104938
6 · The paper itself

Abstract

The DNA binding protein AT-rich interacting domain 3a (ARID3a)

Indexed as

AdultB-LymphocytesCpG IslandsCytokinesDNA-Binding ProteinsFemaleFlow CytometryGene ExpressionHematopoietic Stem CellsHumansInterferon-alphaLigandsMiddle AgedSignal TransductionToll-Like ReceptorsTranscription FactorsARID3A protein, humanCytokinesDNA-Binding ProteinsInterferon-alphaLigandsToll-Like ReceptorsTranscription FactorsARID3aHematopoiesisInnate immunity

Identifiers

PMID32979763
PMCPMC7737244
OpenAlexW3084193253

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.