ArticleHearing research2020
Effects of age on electrophysiological measures of cochlear synaptopathy in humans.
Article in Hearing research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Auditory brainstem response amplitude predicts age-related forward masking temporal-processing deficits in normal-hearing listeners.bioRxiv : the preprint server for biology · 2026Article
- Parallel Age-Related Cochlear Neural Degeneration and Cortical Gain Adaptation in Normal-Hearing Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Age-Related Decline in Neural Phase-Locking to Envelope and Temporal Fine Structure Revealed by Frequency Following Responses: A Potential Signature of Cochlear Synaptopathy Impairing Speech Intelligibility.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- A Systematic Review: State of the Science on Diagnostics of Hidden Hearing Loss.Diagnostics (Basel, Switzerland) · 2025Review
- The relationship between distortion product otoacoustic emissions and audiometric thresholds in the extended high-frequency range.The Journal of the Acoustical Society of America · 2025Article
- The relationship between distortion product otoacoustic emissions and audiometric thresholds in the extended high-frequency range.bioRxiv : the preprint server for biology · 2024Article
- Aging effects on the neural representation and perception of consonant transition cues.Hearing research · 2024Article
- Associations Between Physiological Correlates of Cochlear Synaptopathy and Tinnitus in a Veteran Population.Journal of speech, language, and hearing research : JSLHR · 2023Article
- Article
- Prevention of Noise-Induced Hearing Loss Using Investigational Medicines for the Inner Ear: Previous Trial Outcomes Should Inform Future Trial Design.Antioxidants & redox signaling · 2022Review
- Relations between speech-reception, psychophysical temporal processing, and subcortical electrophysiological measures of auditory function in humans.Hearing research · 2022Article
- The Relative and Combined Effects of Noise Exposure and Aging on Auditory Peripheral Neural Deafferentation: A Narrative Review.Frontiers in aging neuroscience · 2022Review
- Predicting synapse counts in living humans by combining computational models with auditory physiology.The Journal of the Acoustical Society of America · 2022Article
- Use of the auditory brainstem response for assessment of cochlear synaptopathy in humans.The Journal of the Acoustical Society of America · 2021Review
- Effects of age on psychophysical measures of auditory temporal processing and speech reception at low and high levels.Hearing research · 2021Article
- Altered Paired-Click Auditory Brainstem Responses in Normal-Hearing Young Adults With Frequent Loud Sound Exposure.Trends in hearingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Age-related cochlear synaptopathy (CS) has been shown to occur in rodents with minimal noise exposure, and has been hypothesized to play a crucial role in age-related hearing declines in humans. Because CS affects mainly low-spontaneous rate auditory nerve fibers, differential electrophysiological measures such as the ratio of the amplitude of wave I of the auditory brainstem response (ABR) at high to low click levels (WI
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.