Evidence map›Paper›PMID 32979742›Full record

ReviewPathology, research and practice2020

COVID-2019 - A comprehensive pathology insight.

Chandrakumar Shanmugam, Abdul Rafi Mohammed, Swarupa Ravuri, Vishwas Luthra, Narasimhamurthy Rajagopal, Saritha Karre

Open access · greenAbstract readReview
In one paragraph

Review in Pathology, research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

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  12. Acute lung injury-from cannabis to COVID.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Chandrakumar ShanmugamDepartment of Pathology, RVM Institute of Medical Sciences & Research Center (KNR University of Health Sciences) Laxmakkapally, Mulugu, Siddipet Dist., Telangana, 502279, India. Electronic address: dr_chandru2k@yahoo.com.
Abdul Rafi MohammedDepartment of Family Medicine, Locum General Practitioner, NHS, UK & Primary Health Care Corporation, Doha, 26555, Qatar. Electronic address: drmohdrafi@doctors.net.uk.
Swarupa RavuriDepartment of Pathology, Government Medical College, Suryapet, Amaravathi Nagar, Tallagadda, Suryapet, Telangana, 508213, India. Electronic address: swarupa.ravuri@gmail.com.
Vishwas LuthraDepartment of General Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Mehta Road, P.O.Vallah, Amritsar, Punjab, 143501, India. Electronic address: luthra.vishwas@yahoo.com.
Narasimhamurthy RajagopalDepartment of General Medicine, Deccan Medical College and South Central Railway Hospital, Hyderabad, Telangana, 500017, India. Electronic address: lmurthy61@gmail.com.
Saritha KarreDepartment of Pathology, Gandhi Medical College, Musheerabad, Secunderabad, Hyderabad, Telangana, 500003, India. Electronic address: dr_saritha14@yahoo.co.in.
Deccan College of Medical Sciences · INDr. NTR University of Health Sciences · INGandhi Medical College & Hospital · INGovernment Medical College · INInstitute of Medical Sciences · INQatar Airways (Qatar) · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corona virus disease-2019 (COVID-19) caused by severe acute respiratory syndrome corona virus-2 (SARS CoV-2), a highly contagious single stranded RNA virus genetically related to SARS CoV. The lungs are the main organs affected leading to pneumonia and respiratory failure in severe cases that may need mechanical ventilation. Occasionally patient may present with gastro-intestinal, cardiac and neurologic symptoms with or without lung involvement. Pathologically, the lungs show either mild congestion and alveolar exudation or acute respiratory distress syndrome (ARDS) with hyaline membrane or histopathology of acute fibrinous organizing pneumonia (AFOP) that parallels disease severity. Other organs like liver and kidneys may be involved secondarily. Currently the treatment is principally symptomatic and prevention by proper use of personal protective equipment and other measures is crucial to limit the spread. In the midst of pandemic there is paucity of literature on pathological features including pathogenesis, hence in this review we provide the current pathology centered understanding of COVID-19. Furthermore, the pathogenetic pathway is pivotal in the development of therapeutic targets.

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralSARS-CoV-2AFOPARDSCOVID-19PathologySARS CoV-2Therapeutic targets

Identifiers

PMID32979742
PMCPMC7498473
OpenAlexW3087267630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.